李丹丹,黄进,李文伦,侯智文,杜福田,孔庆峰.超声引导多点扇形立体定位单极冷循环射频消融治疗肝癌[J].中国医学影像技术,2009,25(12):2282~2285
超声引导多点扇形立体定位单极冷循环射频消融治疗肝癌
Ultrasound-guided multiple-spot sector stereotaxis in unipolar cooling cycle radiofrequency ablation of hepatic carcinomas
投稿时间:2009-06-22  修订日期:2009-08-24
DOI:
中文关键词:  超声检查  单极冷循环  导管消融  肝肿瘤  体层摄影术,X线计算机
英文关键词:Ultrasonography  Unipolar cooling cycle  Catheter ablation  Liver neoplasms  Tomography, X-ray computed
基金项目:山东省自然基金(Y2008C75)。
作者单位E-mail
李丹丹 潍坊医学院医学影像系,山东 潍坊 261041  
黄进 潍坊市人民医院超声科,山东 潍坊 261041 169276yy@sina.com 
李文伦 潍坊市人民医院超声科,山东 潍坊 261041  
侯智文 潍坊市人民医院超声科,山东 潍坊 261041  
杜福田 潍坊市人民医院肝胆外科,山东 潍坊 261041  
孔庆峰 潍坊医学院医学影像系,山东 潍坊 261041  
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中文摘要:
      目的 评价超声引导多点扇形立体定位单极冷循环射频消融治疗肝癌的效果。 方法 对96例肝癌患者的112个肿瘤,采用多点扇形立体定位法施行超声引导经皮射频消融(RFA)治疗。治疗后15 min行超声造影(CEUS),判断肿瘤是否完全灭活,如灭活不完全则进行重复治疗,治疗后1个月行增强CT(CECT)或CEUS检查评估治疗效果。 结果 112个肿瘤共穿刺293次,成功穿刺269次,穿刺成功率91.81%。治疗后15 min,CEUS示肿瘤无增强。治疗后1个月CT复查,肿瘤体积缩小;89.29%肿瘤CECT无强化,10.71%存在部分强化;CEUS示87.38%肿瘤内无增强,12.62%存在部分增强。 结论 超声引导多点扇形立体定位单极冷循环RFA治疗肝癌疗效可靠,可提高消融治疗对较大肝癌的灭活率。
英文摘要:
      Objective To assess the effect of ultrasound-guided multiple-spot sector stereotaxis in unipolar cooling cycle radiofrequency ablation of hepatic carcinomas. Methods Ninety-six patients with 112 liver malignancies were treated with ultrasound-guided percutaneous radiofrequency ablation using multiple-spot sector stereotaxis method. Conventional multi-section ultrasound scanning was performed to determine the exact location of tumors. Contrast enhanced ultrasound (CEUS) was performed 15 minutes after treatment to determine whether the tumors were completely inactivated. Contrast enhanced CT (CECT) and CEUS were performed 1 month after treatment to evaluate the therapeutic effect. Results A total of 293 punctures were performed for 112 tumors, technical successful rate with a successful rate of puncture was 91.81% (269/293). CEUS showed no blood flow signals in the tumors 15 minutes after therapy. One month after therapy, CT showed the volume of tumors shrunk, no enhancement was found in 100 tumors (100/112, 89.29%), while partial reinforcement was noticed in 12 tumors (10.71%). Meanwhile, CEUS showed no enhancement in 90 tumors (90/103, 87.38%), when partial reinforcement was noticed in 13 tumors (13/103, 12.62%). Conclusion Ultrasound-guided multiple-spot sector stereotaxis unipolar cooling cycle radiofrequency ablation is an effective and reliable method to treat hepatic carcinomas.
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