李文华,陆勇,丁晓毅,何川,周琦,杜联军,刘建军,杨庆铭,陈克敏.成人无症状膝关节软骨病变的磁共振表现与相关临床因素分析[J].中国医学影像技术,2009,25(11):2088~2091
成人无症状膝关节软骨病变的磁共振表现与相关临床因素分析
MRI features and clinical relative factors of asymptomatic adult knee cartilage lesions
投稿时间:2009-03-27  修订日期:2009-08-24
DOI:
中文关键词:  软骨病变  骨关节炎  膝关节  磁共振成像  诊断显像
英文关键词:Cartilage diseases  Osteoarthritis  Knee joint  Magnetic resonance imaging  Diagnostic imaging
基金项目:上海交通大学医学院博士点基金(BXJ0506)。
作者单位E-mail
李文华 山东省青岛市黄岛区中医院放射科,山东 青岛 266500  
陆勇 上海交通大学医学院附属瑞金医院放射科,上海 200025 rj0936@rjh.com.cn 
丁晓毅 上海交通大学医学院附属瑞金医院放射科,上海 200025  
何川 上海交通大学医学院附属瑞金医院骨科,上海 200025  
周琦 上海市伤骨科研究所,上海 200025  
杜联军 山东省青岛市黄岛区中医院放射科,山东 青岛 266500  
刘建军 上海交通大学医学院附属瑞金医院放射科,上海 200025  
杨庆铭 上海交通大学医学院附属瑞金医院骨科,上海 200025  
陈克敏 上海交通大学医学院附属瑞金医院放射科,上海 200025  
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中文摘要:
      目的 借助膝关节软骨磁共振成像(MRI),分析成年志愿者中无症状关节软骨病变的出现规律及临床相关因素。方法 200名无症状志愿者接受软骨MR检查,将局限性软骨信号异常、凹陷或裂隙和(或)伴软骨下骨质水肿定义为软骨病变,分析无症状软骨缺损的主要MRI表现;记录受试者年龄、性别及体重指数(BMI),并结合临床数据进行相关性分析。结果 47名(23.50%)、123个关节面(12.30%)出现软骨病变。病变最好发部位是胫骨内侧平台(17.50%)和股骨内侧髁(14.00%)。MRI表现为软骨内局部异常信号(70.73%)和小凹状裂隙(26.83%),3例为片状不规则缺损(2.44%)。缺损深度均为Noyes ⅡA级以下浅表病变。不同年龄组间软骨病变出现率存在差异,但性别和BMI对软骨病变无显著影响(χ2性别=5.25, P=0.10; χ2BMI=8.22, P=0.07)。结论 膝关节软骨病变在青年人群中普遍存在,其特点为仅累及软骨表层的表浅缺损,且具随年龄增加的趋势。软骨MR成像可早期发现病灶。
英文摘要:
      Objective To analyze the incidence of asymptomatic adult knee cartilage lesions and clinical relative factors with cartilage magnetic resonance imaging (MRI). Methods Cartilage MRI was performed in 200 asymptomatic volunteers. The local cartilage signal intensity (SI) abnormalities, crack and (or) subchondral edema were defined as cartilage lesions, and the manifestations were analyzed. The relative factors (gender, age, body mass index (BMI) and cartilage lesions) were also recorded and analyzed. Results Forty-seven subjects (23.50%, 47/200) were found with cartilage lesions, involving 123 joint facets (12.30%). The most common locations were medial tibial platforms (17.50%) and media femur condyles (14.00%). Local intrachondral SI abnormalities (70.73%) and foveolar crannies (26.83%) were found, and slice-like defects were detected in 3 subjects (2.44%). The degrees of all lesions were less than Noyes ⅡA. There were significant differences of incidence of asymptomatic adult knee cartilage lesions in variant aging groups, but no significant effect of gender and BMI were confirmed on cartilage lesion incidence (χ2gender=5.25, P=0.10; χ2BMI=8.22, P=0.07). Conclusion Asymptomatic knee cartilage lesions like cartilage surface defect are common in people aged 20-40 years, and the incidence is age-correlated. MRI is essential for detecting the cartilage lesions.
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