| 张会萍,杜联芳,李凡,何颖倩.超声造影鉴别诊断肝细胞癌与单发转移性肝癌[J].中国医学影像技术,2009,25(11):2053~2056 |
| 超声造影鉴别诊断肝细胞癌与单发转移性肝癌 |
| Differential diagnosis of isolated hepatocellular carcinoma and metastatic hepatic carcinoma with contrast-enhanced ultrasonography |
| 投稿时间：2009-05-06 修订日期：2009-06-30 |
| DOI： |
| 中文关键词: 超声检查 造影剂 肝肿瘤 肿瘤转移 |
| 英文关键词:Ultrasonography Contrast media Liver neoplasms Neoplasm metastasis |
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| 中文摘要: |
| 目的 探讨超声造影及时间-强度曲线对肝细胞癌(HCC)与转移性肝癌(MHC)单发病灶的鉴别诊断价值。 方法 回顾性分析48例单发性HCC和31例单发性MHC的超声造影图像,应用时间-强度曲线分析各病灶的增强和消退模式,并对比二者的不同。 结果 HCC病灶动脉相多呈粗大紊乱的血管环绕或穿入病灶;MHC病灶动脉相多呈血流散点样充填病灶周边或病灶全部。与HCC相比,MHC的超声造影表现为更快达峰,更快消退,峰值强度稍低,延迟相强度更低;MHC病灶达峰后5、10、30、50和80 s强度均低于HCC;门脉相HCC增强强度消退较MHC慢,MHC于病灶达峰后0~5 s强度迅速下降,HCC则于病灶达峰后10~30 s强度下降较多。 结论 HCC与MHC的超声造影图像特点不同,应用超声造影结合时间-强度曲线分析有助于鉴别单发HCC与MHC。 |
| 英文摘要: |
| Objective To explore the value of contrast-enhanced ultrasonography (CEUS) and time-intensity curve in the differential diagnosis of isolated hepatocellular carcinoma (HCC) and metastatic hepatic carcinoma (MHC). Methods The contrast-enhanced imaging and the time-intensity curve features of 48 patients with isolated HCC and 31 patients with isolated MHC were analyzed retrospectively. Results Most MHC had scattered tiny vessels feeding the periphery or the whole lesity, while most of HCC had chaotic bulky vessels surrounding or entering the focus of tumor. Compared with HCC, MHC had shorter time-to-peak (TTP), quicker regression, lower peak intensity (PI) and more lower intensity in the late phase. The intensity of MHC at 5 s, 10 s, 30 s, 50 s and 80 s after TTP was all lower than the corresponding intensity of HCC. The enhancement intensity of HCC in the portal venous phase generally decreased more slowly than that in MHC. MHC regressed quickly in the first 5 s after TTP to 26.83% (HCC to 8.20%), and HCC regressed faster in 10-30 s after TTP. Conclusion MHC and HCC have different characteristics in CEUS image. Combined with time-intensity curve, CEUS contributes to the differentiation of isolated HCC from isolated MHC. |
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