| 李眉,王振常,戴皓洁,许庆刚,李静.味觉刺激弥散加权成像评价正常涎腺功能[J].中国医学影像技术,2009,25(11):1992~1995 |
| 味觉刺激弥散加权成像评价正常涎腺功能 |
| DWI evaluation of the salivary gland function during gustatory stimulation in healthy subjects |
| 投稿时间：2009-04-18 修订日期：2009-05-22 |
| DOI： |
| 中文关键词: 磁共振成像 表观弥散系数 涎腺 |
| 英文关键词:Magnetic resonance imaging Apparent diffusion coefficient Salivary glands |
| 基金项目: |
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| 中文摘要: |
| 目的 探测MR弥散加权成像(DWI)是否能记录味觉刺激时涎腺弥散系数(ADC)值的变化,并观察味觉刺激前后ADC值的变化。 方法 对17名健康志愿者行1.5T MR检查。DWI序列于静息时采集1次,给予含化维生素C片500 mg之后30 s至23 min左右连续采集。由DWI得到刺激前后涎腺的ADC值,采用重复测量方差分析比较刺激前后的差异。 结果 静息状态颌下腺ADC值(1.26±0.11)×10-3 mm2/s高于腮腺(1.00±0.09)×10-3 mm2/s(P<0.01)。在酸刺激最初的 2 min(0.5~4.5 min)腮腺ADC值 显著升高(P<0.01),颌下腺ADC值 稍升高(P=0.71);之后的7 min(2.5~8.5 min)腮腺ADC值 和颌下腺ADC值 明显下降(P<0.01);之后的9 min ADC值逐渐上升,至16 min(10.5~22.5 min)达高峰。腮腺 明显高于基线值(P<0.01),颌下腺 轻度提高(P=0.02)。 结论 DWI可以无创地评价涎腺功能变化,味觉刺激后ADC值显示出三个阶段的变化,可能对早期发现涎腺功能改变起到一定的作用 |
| 英文摘要: |
| Objective To evaluate the function of salivary glands of healthy volunteers during gustatory stimulation with MR diffusion-weighted imaging (DWI). Methods Seventeen healthy subjects underwent 1.5T MR examination. DWI sequence was performed once at rest and continuously repeated over a mean period of 23 min during salivary stimulation with 500 mg ascorbic acid given orally. Results At rest, ADC value of submandibular glands was higher than that of parotid glands (P<0.01). During the first 2 min (0.5－4.5 min) of salivary stimulation, ADC value of parotid glands increased obviously (P<0.01), but not the submandibular glands (P=0.71). Then ADC was significantly decreased in both glands at 7 min (2.5－8.5 min). During the following 9 min, a steady increase in ADC from the baseline value was noted for the parotid glands (P<0.01), and peak ADC appeared at 16 min (10.5－22.5 min) after the start of gustatory stimulation. ADC of the submandibular glands did not increase significantly after the start of gustatory stimulation compared with the ADC at baseline (P=0.02). Conclusion The functional changes in the salivary glands during gustatory stimulation can be evaluated with DWI noninvasively, and DWI may contributes to the early detection of functional change of salivary glands. |
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