| 许杨青,陈欣林,谢明星,陈佩文,张磊,陆兆龄,胡蕾.大鼠胎盘超声造影时间-强度曲线特征初步观察[J].中国医学影像技术,2009,25(11):1972~1974 |
| 大鼠胎盘超声造影时间-强度曲线特征初步观察 |
| Features of time-intensity curve of contrast-enhanced ultrasonography of rat placenta |
| 投稿时间：2008-12-09 修订日期：2009-02-16 |
| DOI： |
| 中文关键词: 胎盘 超声造影 时间-强度曲线 动物实验 |
| 英文关键词:Placenta Contrast-enhanced ultrasonography Time-intensity curves Animal experimentation |
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| 摘要点击次数: 2588 |
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| 中文摘要: |
| 目的 观察大鼠胎盘超声造影灌注时间-强度曲线的特征,以及其特征是否可反映子宫-胎盘血流循环的基本特点。 方法 妊娠晚期的Wistar大鼠20只,在超声诊断仪CPS成像系统下选择每只孕鼠腹中的一只胎鼠的胎盘行超声造影检查。在大鼠胎盘的动脉导管和绒毛间隙区分别建立感兴趣区,得到随时间变化的强度Excel文件后,进行伽玛函数拟合,根据拟合的曲线方程计算造影剂到达时间(AT)、达峰时间(PIT)、峰值强度(PI)、曲线下面积(AUC)。 结果 大鼠胎盘动脉导管感兴趣区建立的时间-强度曲线较绒毛间隙建立的曲线形态更宽阔。AT、PIT、PI及AUC在两部位间比较差异均有统计学意义(P＜0.05)。 结论 超声造影定量时间-强度曲线能够反映大鼠子宫-胎盘血流循环的基本特点。 |
| 英文摘要: |
| Objective To observe features of time-intensity curve (TIC) of contrast-enhanced ultrasonography of rat placenta, and whether these features can reflect characteristics of blood concentration and flow in placental central canal and intervillous lacuna. Methods Twenty pregnant rats were selected and one of placentas was selected for examination with contrast enhanced ultrasonography. Regions of interest (ROIs) were set up in arterial canal and intervillous lacuna. Correspondent parameters of TIC included arriving time (AT), time to peak intensity (PIT), peak signal intensity (PI) and area under the curve (AUC). Results Compared with intervillous lacuna, curve pattern was wider in artery canal. AT, PIT, PI and AUC were all statistically different between artery canal and intervillous lacuna. Conclusion TIC can reflect the feature of blood concentration in placental central arterial canal and intervillous space of rat. |
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