| 何小江,黄劲雄,陈贵兵,俞浩,吴华.99mTc-奥曲肽显像和X线钼靶诊断乳腺癌[J].中国医学影像技术,2009,25(10):1892~1895 |
| 99mTc-奥曲肽显像和X线钼靶诊断乳腺癌 |
| 99mTc-octreotide scintigraphy and planar X-ray mammography diagnosis of breast cancer |
| 投稿时间：2009-03-09 修订日期：2009-06-12 |
| DOI： |
| 中文关键词: 放射性核素显像 X线钼靶 乳腺肿瘤 |
| 英文关键词:Radionuclide imaging X-ray mammography Breast neoplasms |
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| 中文摘要: |
| 目的 比较99mTc-奥曲肽显像和X线钼靶诊断乳腺癌的临床应用价值。 方法 32例临床怀疑乳腺癌的女性患者,均进行99mTc-奥曲肽显像和X线钼靶摄影,以手术病理结果为标准,比较二者对乳腺癌的诊断效能。 结果 99mTc-奥曲肽显像和X线钼靶摄影诊断乳腺癌的灵敏度分别为91.67%、66.67%(χ2=4.54,P<0.05),特异性分别为100%、37.50%(χ2=4.65,P<0.05),准确性分别为93.75%、59.38%(χ2=10.54,P<0.05),阳性预测值分别为100%、76.19%(χ2=5.93,P<0.05),阴性预测值分别为80.00%、27.27%(χ2=3.92,P<0.05)。联合两种方法诊断的灵敏度、特异性、准确性、阳性预测值和阴性预测值分别为95.83%、100%、96.88%、82.14%和47.06%。 结论 99mTc-奥曲肽显像对乳腺癌的诊断效能高于X线钼靶摄影,两者联合可进一步提高诊断效能。 |
| 英文摘要: |
| Objective To compare the value of 99mTc-octreotide scintigraphy and planar X-ray mammography in the diagnosis of breast cancer. Methods A total of 32 patients with suspected breast cancer were enrolled into this study. All patients underwent 99mTc-octreotide scintigraphy and planar X-ray mammography. The diagnostic efficiency of 99mTc-octreotide scintigraphy and planar X-ray mammography were compared based on the post-surgery pathology. Results The sensitivity of 99mTc-octreotide scintigraphy and planar X-ray mammography in the diagnosis of breast cancer was 91.67% and 66.67%, the specificity was 100% and 37.50%, the accuracy was 93.75% and 59.38%, respectively. Combining 99mTc-octreotide scintigraphy with planar X-ray mammography, the sensitivity, specificity, accuracy, positive predicting values and negative predicting values for breast cancer was 95.83%, 100%, 96.88%, 82.14% and 47.06%, respectively. Conclusion The diagnostic efficiency of 99mTc-octreotide scintigraphy for breast cancer is superior to planar X-ray mammography. 99mTc-octreotide scintigraphy combined with planar X-ray mammography, the diagnostic efficiency for breast cancer will be further improved. |
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