刘方义,于晓玲,梁萍,王旸,程志刚,于杰.植入式水冷915 MHz与2450 MHz微波消融的猪活体肝脏的实验对比[J].中国医学影像技术,2009,25(10):1765~1768
植入式水冷915 MHz与2450 MHz微波消融的猪活体肝脏的实验对比
Comparison of implanted cooled-shaft 915 MHz and 2450 MHz microwave ablation of in vivo porcine livers
投稿时间:2009-01-07  修订日期:2009-06-12
DOI:
中文关键词:  导管消融  肝脏  动物实验
英文关键词:Catheter ablation  Liver  Animal experiment
基金项目:
作者单位E-mail
刘方义 中国人民解放军总医院超声科,北京 100853  
于晓玲 中国人民解放军总医院超声科,北京 100853 dyuxl301@yahoo.com.cn 
梁萍 中国人民解放军总医院超声科,北京 100853  
王旸 中国人民解放军总医院超声科,北京 100853  
程志刚 中国人民解放军总医院超声科,北京 100853  
于杰 中国人民解放军总医院超声科,北京 100853  
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中文摘要:
       目的 对比植入式水冷915 MHz和2450 MHz微波在活体猪肝脏消融实验中的消融范围及热场特性。方法 根据频率不同分两组实验。915 MHz和2450 MHz微波天线沿特制支架插入活体猪肝脏后,平行天线裂隙旁开5 mm、10 mm、15 mm、20 mm 间距的A(5,0)、B(10,0)、C(15,0)、D(20,0)四点分别放置测温针,均以60 W、600 s条件辐射,计算机采集测温数据,消融后测量消融区范围并比较两组消融范围的大小,分析温升曲线并比较两组的温升速率及所达最高温度。结果 915 MHz微波较2450 MHz微波在活体猪肝消融中可获得更大的消融横径和纵径;915 MHz微波和2450 MHz微波两者距离天线越近的位点温升速率越快,所达最高温度亦越高;对应B、C、D点上915 MHz微波较2450 MHz微波具有更快的温升速率及更高的温度。结论 915 MHz微波与2450 MHz微波相比,915MHz微波可获得更大的消融范围,具有更高的热效率。
英文摘要:
      Objective To compare the difference of implanted cooled-shaft with 915 MHz and 2450 MHz microwave in ablation area and the characteristics of temperature field in porcine livers in vivo. Methods Ablations were performed with 915 MHz and 2450 MHz, and were divided into two groups accordingly. The microwave antenna was inserted into porcine liver in vivo and the thermal needles were placed in parallel 5 mm, 10 mm, 15 mm, 20 mm, away from the antenna slit. The temperature data were collected with computer when the microwave ablation was started with the same energy of 60 W 600 s. After ablations, sizes of the ablation zones and the temperature curves were compared between the two groups. Results Compared with 2540 MHz microwave, 915 MHz microwave had larger coagulation length and width, faster temperature ascending rate and higher temperature in corresponding points. Conclusion In porcine livers in vivo, compared with 2450 MHz microwave, larger coagulation zone and faster temperature ascending rate can be obtained with 915 MHz microwave.
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