| 黄丽萍,唐少珊,解丽梅,王鹏,刘守君.原发性肝细胞癌超声造影表现与微血管密度的相关性[J].中国医学影像技术,2009,25(9):1645~1647 |
| 原发性肝细胞癌超声造影表现与微血管密度的相关性 |
| Contrast-enhanced ultrasonography appearance of primary hepatocellular carcinoma and the correlation with microvessel density |
| 投稿时间：2009-03-03 修订日期：2009-05-15 |
| DOI： |
| 中文关键词: 肝肿瘤 造影剂 超声检查 微血管密度 |
| 英文关键词:Liver neoplasms Contrast media Ultrasonography Microvessel density |
| 基金项目:辽宁省教育厅基金(2008T210)。 |
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| 摘要点击次数: 2562 |
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| 中文摘要: |
| 目的 探讨原发性肝细胞癌(HCC)的造影增强时间-强度曲线参数与肿瘤微血管密度(MVD)的相关性。 方法 回顾性分析经病理证实为HCC的24例患者HCC超声造影增强时间-强度曲线参数(增强时间、上升斜率、相对峰值强度、峰值增强率、下降斜率),同时检测肿瘤的MVD,分析造影增强时间-强度曲线参数与MVD的相关性。 结果 中低分化HCC组MVD大于高分化HCC组(P<0.05)。HCC的相对峰值强度、下降斜率与MVD计数相关(P<0.05),相关系数分别为0.44、0.50。 结论 HCC造影增强时间-强度曲线的相对峰值强度、下降斜率可反映肿瘤微血管形成,不同分化程度HCC的MVD差异显著。 |
| 英文摘要: |
| Objective To investigate the relationship between the parameters of contrast enhanced ultrasonography (CEUS) time-intensity curve of primary hepatocellular carcinoma (HCC) and microvessel density (MVD). Methods Twenty-four patients with confirmed HCC underwent CEUS, the parameters of time-intensity curve were analyzed and the MVD was counted, and the correlation between the parameters and the MVD was analyzed. Results MVD number of moderately to poorly differentiated HCCs was larger than that of well differentiated HCCs (P<0.05). The relative peak intensity and falling slope of time-intensity curve correlated with MVD (r=0.44, 0.50, P=0.03, 0.01, respectively). Conclusion The relative peak intensity and falling slope of time-intensity curve correlate with MVD. The difference of MVD among different differentiated HCCs is obvious. |
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