| 马跃,任莹,富西湖,石喻,乞文旭,郭启勇.不同b值磁共振扩散加权成像鉴别诊断胰腺癌与慢性肿块型胰腺炎[J].中国医学影像技术,2009,25(9):1641~1644 |
| 不同b值磁共振扩散加权成像鉴别诊断胰腺癌与慢性肿块型胰腺炎 |
| Different b values on DWI in differential diagnosis of pancreatic carcinoma and chronic mass-forming pancreatitis |
| 投稿时间：2009-02-06 修订日期：2009-04-21 |
| DOI： |
| 中文关键词: 胰腺肿瘤 胰腺炎 磁共振成像 扩散加权成像 表观扩散系数 |
| 英文关键词:Pancreatic neoplasms Pancreatitis Magnetic resonance imaging Diffusion weighted imaging Apparent diffusion coefficient |
| 基金项目: |
|
| 摘要点击次数: 2238 |
| 全文下载次数: 864 |
| 中文摘要: |
| 目的 分析不同b值下胰腺癌、慢性肿块型胰腺炎与正常胰腺组织ADC值及其差值(DADC值)变化情况,探讨用于鉴别胰腺癌、慢性肿块型胰腺炎的最适b值。方法 对15例胰腺癌(Ⅰ组)、4例慢性肿块型胰腺炎患者(Ⅱ组)及15名胰腺正常的志愿者(Ⅲ组)行磁共振扩散加权成像(DWI),b值分别为333、667、1000 s/mm2。测量各b值下癌区、慢性炎症区和正常胰腺区的ADC值,并对不同b值时三种组织ADC值及不同组织间DADC值的变化进行分析。结果 相同b值时胰腺癌区ADC值低于慢性炎症肿块区和正常胰头区。不同b值时各组内ADC值差异均有统计学意义(P<0.05),随b值增大,三组的ADC值均有下降,其中胰腺癌区平均下降率最低(15.66%和5.19%)。b=333和667 s/mm2时,胰腺癌区与慢性炎症肿块区、胰腺癌区与正常胰头区的ADC值差异均有统计学意义(P<0.05)。不同b值时,胰腺癌区与慢性炎症肿块区、胰腺癌区与正常胰头区两配对组组内的DADC值差异均有统计学意义(P<0.05),且b=333 s/mm2时各配对组组内的DADC值最大。结论 在一定范围内小b值有助于胰腺癌与慢性肿块型胰腺炎的鉴别诊断。 |
| 英文摘要: |
| Objective To investigate the changes of ADC at different b values in pancreatic carcinoma, chronic mass-forming pancreatitis and normal pancreas, and to evaluate the optimal b value in differentiating diagnosis. Methods Diffusion-weighted imaging (DWI) was performed in 15 patients of pancreatic carcinoma (group Ⅰ), 4 with chronic mass-forming pancreatitis (group Ⅱ) and 15 normal volunteers (group Ⅲ) with the b value of 333, 667 and 1000 s/mm2, respectively. The ADC values of carcinous regions, inflammatory mass and normal pancreatic head were measured, and the difference of ADC (DADC) in different tissues of each patient was calculated. Results At the same b value, ADC value of carcinous regions was lower than those of inflammatory mass and normal pancreatic head. ADC values at three different b values in the same tissue were statistically different (P<0.05). As the b value increased, the ADC value decreased, and in carcinous regions the decreased rates of ADC value were the lowest (15.66% and 5.19%). When b value was 333 and 667 s/mm2, ADC values of carcinous regions were statistically different from those of the inflammatory mass and normal pancreatic head (P<0.05). There were statistically differences of DADC values between pancreatic carcinoma and chronic mass-forming pancreatitis, also between pancreatic carcinoma and normal pancreas detected at all three different b values (P<0.05). When b value was 333 s/mm2, DADC values were significant higher than those detected at other two b values. Conclusion Smaller b value is helpful for differentiating diagnosis of pancreatic carcinoma and chronic mass-forming pancreatitis. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
