| 杨根东,陆普选,詹能勇,曹义,张莉萍,李苑.艾滋病并发肺隐球菌病的影像学诊断[J].中国医学影像技术,2009,25(9):1581~1583 |
| 艾滋病并发肺隐球菌病的影像学诊断 |
| Imaging manifestations of pulmonary cryptococcosis in AIDS patients |
| 投稿时间：2009-04-01 修订日期：2009-05-22 |
| DOI： |
| 中文关键词: 获得性免疫缺陷综合征 肺隐球菌病 诊断显像 |
| 英文关键词:Acquired immunodeficiency syndrome Pulmonary cryptococcosis Diagnostic imaging |
| 基金项目:深圳市卫生局重点科技项目基金(SZW2006-15)。 |
|
| 摘要点击次数: 2253 |
| 全文下载次数: 897 |
| 中文摘要: |
| 目的 分析艾滋病(AIDS)并发肺隐球菌病(PC)的影像学表现。方法 回顾性分析5例经证实的AIDS并发PC的胸部X线与CT扫描资料,结合文献分析其影像学特点。结果 本组5例的影像学表现有:①结节或肿块型:共2例,1例为右肺中叶外侧段单发软组织密度结节,直径约2.7 cm,周围可见晕征、毛刺征及分叶征等;1例为两肺外周多发软组织密度结节或肿块,大小1.1~4.3 cm,结节内可见空洞但未见钙化;②斑片浸润型:共2例,分别位于右肺中叶、下叶及左肺上叶,实变内可见空气支气管征,经抗隐球菌治疗后病变吸收;③弥漫混合型:1例,呈两肺斑片影、结节影和粟粒影混杂存在。本组5例中2例同时合并隐球菌性脑膜炎征象,1例合并胸腔积液和纵隔淋巴结肿大。结论 AIDS并发PC的胸部影像学表现复杂,缺乏特异性。当AIDS合并肺部外周结节和(或)肿块、斑片状浸润或多形态混杂病变并除外肺癌或结核等其他感染时,应考虑本病可能。本病确诊有赖于多途径查找到隐球菌。 |
| 英文摘要: |
| Objective To analyze imaging manifestations of pulmonary cryptococcosis (PC) in acquired immunodeficiency syndrome (AIDS) patients. Methods The chest X-ray and CT findings of 5 patients with PC in AIDS confirmed by pathological examinations were retrospectively analyzed, and the relative literatures were reviewed. Results The imaging manifestations were classified into the following three types: ①Nodule or mass (n=2). Including one presented as a solitary soft tissue density nodule about 2.7 cm in diameter, located in the lateral segment of right lung middle lober with Halo sign, spicular sign and lobulated sign at the edge of the nodule, and the other as multiple soft tissue density nodules or masses varied from 1.1—4.3 cm in diameter, mainly located in the peripheral zone of lung with cavity in some nodules; ②Patchy infiltration (n=2). The location of 1 abnormality was in the middle and inferior lobers of right lung, and the other was in the upper lober of left lung. Air-bronchogram could be found in consolidations and the lesions were absorbed partly after anti-cryptococcosis therapy; ③Diffuse mixed pattern (n=1). The abnormalities were mixed patchies, nodules and military shadows in bilateral lungs. In this group, cryptococcus neoformans meningitis was detected in 2 patients; pleural effusion and mediastinum lymph nodes enlargement were also found in 1 patient. Conclusion The imaging manifestations of PC in AIDS are various and short of specificity. PC in AIDS should be considered if the nodules and (or) masses are found located in the peripheral zone of lung with patchy-infiltration or various mixed lesions when lung cancer and some infections as tuberculosis can be excepted. PC in AIDS will be confirmed when cryptococcus neoformans are positive. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
