| 贾承晔,于丽娟,段钰.18F-FDG PET/CT对非小细胞肺癌治疗策略的影响[J].中国医学影像技术,2009,25(8):1473~1476 |
| 18F-FDG PET/CT对非小细胞肺癌治疗策略的影响 |
| 18F-FDG PET/CT in monitoring recurrence and metastasis of gynecological malignant tumor |
| 投稿时间：2008-12-03 修订日期：2009-02-13 |
| DOI： |
| 中文关键词: 生殖器肿瘤,女性 复发 肿瘤转移 体层摄影术,发射型计算机 体层摄影术,X线计算机 氟脱氧葡萄糖F18 |
| 英文关键词:Genital neoplasms, female Recurrence Neoplasm metastasis Tomography, emission-computed Tomograpy, X-ray computed Fluorodeoxyglucose F18 |
| 基金项目: |
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| 中文摘要: |
| 目的 探讨18F-FDG PET/CT在妇科恶性肿瘤诊断及综合治疗后复发和转移中的临床价值。方法 对接受18F-FDG PET/CT显像并具有完整临床资料的83例妇科肿瘤病例进行回顾性分析,其中19例为初诊患者,64例为恶性肿瘤综合治疗后患者。结果 ①19例初诊患者中,PET/CT显像均为阳性,其中1例为假阳性,诊断准确性为94.74%(18/19);64例治疗后患者中,PET/CT诊断肿瘤复发或残余的敏感性、特异性和准确性分别为95.24%(20/21)、100%(43/43)和98.44%(63/64);②PET/CT诊断淋巴结转移的准确率分别为腹主动脉旁淋巴结98.78%、盆腔淋巴结97.56%、腹股沟淋巴结98.78%;③11例接受2次及2次以上PET/CT检查的患者中,6例根据PET/CT结果更改治疗方案。结论 18F-FDG PET/CT可以早期发现可疑复发或转移病灶,在检测远处转移和小淋巴结转移方面具有独特优势,是监测妇科恶性肿瘤复发和转移的有效检查方法,对于临床制定和调整治疗方案有重要意义。 |
| 英文摘要: |
| Objective To assess the clinical value of 18F-FDG PET/CT in monitoring recurrence and metastasis of gynecological malignant tumor after combination therapy. Methods A total of 83 patients of gynecological tumor underwent PET/CT, including 19 first time patients and 64 after comprehensive treatment, and the data were analyzed retrospectively. Results ①In 19 first visit patients, PET/CT were 18 true positive but one false positive, the accuracy of PET/CT was 94.74% (18/19). In 64 patients after comprehensive treatment, the sensitivity, specificity and accuracy of PET/CT in monitoring recurrence and metastasis were 95.24% (20/21), 100% (43/43) and 98.44% (63/64), respectively. ②The accuracy of PET/CT in diagnosis of lymph nodes metastasis was 98.78% for paraaortic nodes, 97.56% for pelvic nodes and 98.78% for groin nodal metastasis. ③Treatment plans were modified in 6 of 11 patients who undertook PET/CT for two or more than two times. Conclusion 18F-FDG PET/CT imaging can detect the recurrence and metastasis of gynecological malignant tumor in the early stage and has distinct superiority in detecting distant metastasis and small lymph nodes metastasis. It has great significance in monitoring the recurrence and metastasis of gynecological malignant tumor and contributes to the treatment plans. |
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