支联合,张洁,单保慈.基于提升小波变换的功能MRI数据分析[J].中国医学影像技术,2009,25(7):1286~1288
基于提升小波变换的功能MRI数据分析
Analysis of functional MRI data based on lifting wavelet transform
投稿时间:2009-02-04  修订日期:2009-04-04
DOI:
中文关键词:  磁共振成像  提升小波分析  频谱分析  相关分析
英文关键词:Magnetic resonance imaging  Lifting wavelet analysis  Frequency analysis  Correlation analysis
基金项目:周口师范学院博士科研启动基金和河南省教育厅自然科学研究计划项目(2007310024、2008A180040)。
作者单位E-mail
支联合 周口师范学院物理与电子工程系,河南 周口 466000  
张洁 北京中医药大学东直门医院放射科, 北京 100700  
单保慈 中国科学院高能物理研究所核分析技术重点实验室,北京 100049 shanbc@mail.ihep.ac.cn 
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中文摘要:
       目的 构建一种快速的fMRI数据小波分析方法。方法 用提升小波变换代替平稳小波变换分解fMRI数据,以分离其实验响应信号和干扰信号,再由频谱分析识别实验响应信号所在的小波尺度,并只对实验响应信号所在的小波尺度进行重构,最后对重构信号进行相关分析来检测激活。结果 分析视觉实验数据显示,在显著性水平为α<10-6时,本文基于提升小波变换的方法比未去噪的相关分析方法更灵敏,而消耗时间比基于平稳小波变换的方法大幅度减少。同时本文方法只需24个数据点即可进行小波重构,而基于平稳小波变换的方法则需要256个数据点。结论 本文为fMRI数据提出了一种既能快速分析又能有效压缩的小波分析方法。
英文摘要:
      Objective To design a fast method based on wavelet analysis for fMRI data. Methods Lifting wavelet decomposition instead of stationary wavelet decomposition was utilized to separate paradigm responsive signal and confound ones in fMRI data, while frequency analysis was used to find out the wavelet scales in which paradigm responsive signal existed, then reconstructed signal from these scales was subjected to correlation analysis for actived pixels. Results Analyzing visual fMRI data revealed that when the significant level was α<10-6, the proposed method gave more sensitive results than correlation analysis, but process time decreased on a large scale compared with the one based on the stationary wavelet transform. At the mean time, the proposed method only used 24 timepoints of data for wavelet reconstruction while one based on stationary wavelet transform used 256 timepoints of data. Conclusion The proposed method is the fast one based on wavelet transform for analyzing fMRI data, which also gives an effective technique for compressing fMRI data.
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