| 徐莉,梁长虹,刘再毅,赵振军,黄飚,曾琼新,萧远球.在体肝脏3.0T质子MRS匀场与抑水信度研究及相关分析[J].中国医学影像技术,2009,25(7):1208~1210 |
| 在体肝脏3.0T质子MRS匀场与抑水信度研究及相关分析 |
| Reliability and correlation of in vivo heptic shimming of liver and water suppression with 3.0T proton MRS |
| 投稿时间：2008-11-24 修订日期：2009-01-05 |
| DOI： |
| 中文关键词: 肝脏 磁共振波谱 单体素 信度 |
| 英文关键词:Liver Magnetic resonance spectroscopy Single volume Reliability |
| 基金项目:广东省自然科学基金(5001199),广东省科技计划项目(2005B10401040、2007B31515008),广东省医学科学技术研究基金(A2005018),国家自然科学基金(30800269)。 |
| 作者 | 单位 | E-mail | | 徐莉 | 广东省人民医院放射科,广东省医学科学院,南方医科大学附属华南医院,广东 广州 510080 | | | 梁长虹 | 广东省人民医院放射科,广东省医学科学院,南方医科大学附属华南医院,广东 广州 510080 | cjr.lchh@vip.163.com | | 刘再毅 | 广东省人民医院放射科,广东省医学科学院,南方医科大学附属华南医院,广东 广州 510080 | | | 赵振军 | 广东省人民医院放射科,广东省医学科学院,南方医科大学附属华南医院,广东 广州 510080 | | | 黄飚 | 广东省人民医院放射科,广东省医学科学院,南方医科大学附属华南医院,广东 广州 510080 | | | 曾琼新 | 广东省人民医院放射科,广东省医学科学院,南方医科大学附属华南医院,广东 广州 510080 | | | 萧远球 | 广东省人民医院放射科,广东省医学科学院,南方医科大学附属华南医院,广东 广州 510080 | |
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| 中文摘要: |
| 目的 探讨在体肝脏3.0T单体素PRESS序列质子MRS自动匀场线宽(LW)和抑水率(WS)的信度及二者的相关性。 方法 采用GE Signa Excite HD 3.0T超导MR扫描仪,8通道相控阵线圈。1H-MRS采集参数为TR/TE 1500/30 ms,NSA 64,VOI 2 cm×2 cm×2 cm。波谱常规预扫描,记录LW和WS后进行波谱采集,然后重复执行一次得到另外一组LW及WS数据共计38组。计算两次LW和WS组内相关系数(ICC)、变异系数(CV)及两次重复测量结果之间的显著性,并对LW和WS行等级相关分析。 结果 ①前后两次波谱常规预扫描LW和WS的ICC分别为0.862、0.961(P均<0.0001);CV分别为0.20、0.18、0.09、0.08。两次LW(t=1.106, P=0.276)和WS(t=—1.349, P=0.186)差异均无统计学意义。②前后两次LW和WS相关系数为-0.659,-0.485(P均<0.0001)。 结论 ①在体肝脏单体素3.0T质子波谱自动匀场与抑水信度较好,匀场与抑水效果差者相同部位重复进行匀场与抑水达到较好效果的预期成功率低。重复测量时匀场线宽的变异程度较抑水率大。②匀场效果与抑水效果呈中等程度相关,匀场效果好的更容易达到良好的抑水,从而有可能在采集中得到高分辨的可析性波谱。 |
| 英文摘要: |
| Objective To assess the reliability of auto-shimming line width (LW) and water suppression rate (WS), and the correlation between them. Methods GE Signa Excite HD 3.0T system and eight-channel torso phased-array coils with PRESS sequence were performed in 38 volunteers. Liver spectra were collected with TR of 1500 ms, TE of 30 ms, VOI of 2 cm×2 cm×2 cm, NSA of 64 times. Spectroscopy routine auto-shimming pre-scanning program was executed and the values of LW and WS were recorded. Then another spectroscopy routine auto-shimming pre-scanning program was performed repeatedly and 38 groups of data were obtained totally. Intra-class correlation coefficients (ICC), coefficient of variation (CV) and significance test were conduced on 38 groups of LW and WS data. Spearman rank correlation analysis was used to assess the correlation of LW and WS. Results ①The ICC of LW and WS was 0.862 and 0.961 (both P＜0.0001), respectively, while the value of CV was 0.20, 0.18, 0.09 and 0.08, respectively. Significant difference was not observed; ②The value of correlation coefficient was —0.659, —0.485 (both P＜0.0001), respectively. Conclusion ①The reliability is excellent for in vivo liver 3.0T 1H-MRS and WS appears relatively stable; ②Indexes of LW correlate with WS moderately, and it seems the smaller the value of LW is, the easier to achieve higher WS. |
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