| 聂芳,陈慧,陈斌娟,车岩.股动脉内-中膜厚度、僵硬度及血流动力学参数评价2型糖尿病患者下肢血管病变[J].中国医学影像技术,2009,25(7):1189~1191 |
| 股动脉内-中膜厚度、僵硬度及血流动力学参数评价2型糖尿病患者下肢血管病变 |
| Clinical evaluation of peripheral vascular disease with wall thickness, stiffness and hemodynamics of femoral artery in type 2 diabetes mellitus |
| 投稿时间：2008-12-02 修订日期：2009-02-24 |
| DOI： |
| 中文关键词: 僵硬度 内-中膜厚度 血流动力学 下肢血管病变 糖尿病 |
| 英文关键词:Stiffness Intima-media thickness Hemodynamics Peripheral vascular diseases Diabetes mellitus |
| 基金项目:兰州市科技局科研基金(2008-1-87)。 |
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| 中文摘要: |
| 目的 探讨股动脉内-中膜厚度(FA-IMT)、僵硬度β及血流动力学参数与2型糖尿病患者下肢血管病变(PVD)的相关性。 方法 151例2型糖尿病患者分为PVD症状组(具有间歇性跛行和(或)静息性腿痛)和无PVD症状组。使用二维超声测量FA-IMT;彩色流速流量定量技术测量股动脉收缩期内径及舒张期内径,收缩期峰值血流速度(PSV)和舒张末期血流速度(EDV)。比较FA-IMT、股动脉僵硬度β (FA-stiffness β)、PSV、EDV在两组中的差异,多元回归分析FA-IMT、FA-stiffness β、PSV、EDV与PVD症状的相关性。结果 与无PVD症状组比较,PVD症状组FA-IMT、FA-stiffness β增高(P＜0.01),PSV、EDV减低(P＜0.01)。PVD症状组中,FA-IMT与FA-stiffness β无相关性(P＝0.10);病程、FA-stiffness β,PSV,EDV和下肢PVD症状相关;而年龄,性别、FA-IMT及与PVD症状无相关性。 结论 FA-stiffness β在2型糖尿病患者PVD的临床评价中发挥着更重要作用。 |
| 英文摘要: |
| Objective To evaluate the relationship between femoral artery intima-media thickness (FA-IMT), stiffness, hemodynamics factors of femoral artery and peripheral vascular disease (PVD) in type 2 diabetes mellitus. Methods According to the presence of PVD, 151 patients with type 2 diabetes were divided into PVD group and non-PVD group. FA-IMT was tested with 2D ultrasound. Ds, Dd, PSV, EDV were observed with color flow rate and volume quantitative technology. FA-IMT, FA-stiffness β, peak systolic velocity (PSV) and end diastolic velocity (EDV) were compared between the two groups. Results Compared with non-PVD group, FA-IMT and FA-stiffness β increased in PVD group (P＜0.01), whereas PSV and EDV decreased in PVD group (P＜0.01). There was no relationship between FA-stiffness β and FA-IMT in PVD group (P=0.01). Multiple Logistic regression indicated the presence of PVD symptoms associated closely with FA-stiffness β, PSV, EDV and duration of diabetes. Conclusion Stiffness β plays an important role in the clinical evaluation of type 2 diabetes mellitus. |
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