李静,李澄,王苇.纤维束示踪成像技术定量评价急性期脑出血锥体束损伤[J].中国医学影像技术,2009,25(7):1163~1166
纤维束示踪成像技术定量评价急性期脑出血锥体束损伤
Diffusion tensor tractography quantitative assessment of the damage of corticospinal tract in acute intracerebral hemorrhage
投稿时间:2009-01-05  修订日期:2009-03-02
DOI:
中文关键词:  纤维束示踪成像技术  锥体束  脑出血
英文关键词:Diffusion tensor tractography  Corticospinal tract  Intracerebral hemorrhage
基金项目:
作者单位E-mail
李静 江苏大学基础医学与医学技术学院影像系,江苏 镇江 212001
扬州市第一人民医院影像科,江苏 扬州 225001 
 
李澄 扬州市第一人民医院影像科,江苏 扬州 225001 cjr.licheng@vip.163.com 
王苇 扬州市第一人民医院影像科,江苏 扬州 225001  
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中文摘要:
       目的 探讨白质纤维束示踪成像技术定量评价急性期脑出血患者锥体束损伤情况的可行性。方法 对我院32例急性期脑出血患者行磁共振扩散张量成像,应用日本东京大学Volume One 1.64和diffusion Tensor Visualizer Ⅱ(dTVⅡ)软件进行白质纤维束的三维重建,通过感兴趣区的设置观察患侧皮质脊髓束(CST)的受压、推移及破坏情况,并由软件计算获得患侧相对剩余CST条目数。结果 32例患者的纤维束示踪图像均可不同程度观察到患侧CST受血肿压迫推移或破坏中断情况,且患侧相对剩余CST条目数与起病时Fugl-Meyer评分之间具有较高的相关性(r=0.75,P<0.01)。结论 白质纤维束示踪成像技术可以定量评价急性期脑出血患者CST的损伤情况。
英文摘要:
      Objective To investigate the value of diffusion tensor tractography (DTT) quantitative assessment of corticospinal tract (CST) damage in acute intracerebral hemorrhage (ICH). Methods Thirty-two patients were enrolled in this study. DTT was obtained in early stage of ICH. The CST was reconstructed with Volume One 1.64 and diffusion Tensor Visualizer (dTV) software from Tokyo University. The compression, the displacement, the destruction, and the relative remaining number of the CST were calculated. Results The compression, the displacement and the destruction of the CST were observed in DTT images in all patients. The correlation coefficient between remaining number of the CST and score of Fugl-Meyer after the onset of ICH was 0.75 (P<0.01). Conclusion DTT can quantitatively evaluate the state of CST injury in acute ICH.
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