秦文,李坤成,于春水,张帆.重复时间和场强对脑白质弥散张量成像定量研究的影响[J].中国医学影像技术,2009,25(7):1127~1130
重复时间和场强对脑白质弥散张量成像定量研究的影响
Effects of repetition time and field strength on diffusion indices of brain white matter
投稿时间:2008-12-31  修订日期:2009-03-28
DOI:
中文关键词:  弥散张量成像  重复时间  场强  信噪比
英文关键词:Diffusion tensor imaging  Repetition time  Field strength  Signal to noise ratio
基金项目:国家自然科学基金(30470519),北京市科技新星计划(2005B21)。
作者单位E-mail
秦文 Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China  
李坤成 Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China likuncheng1955@yahoo.com.cn 
于春水 Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China  
张帆 
 
 
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中文摘要:
      
英文摘要:
      Objective To observe whether repetition time (TR) and field strengths have effects on diffusion indices of brain white matter. Methods Seven rhesuses underwent diffusion tensor MR imaging (DT-MRI) with a series of TRs (from 500 to 6000 ms) at 1.5T and 3.0T MR scanners, respectively. The mean diffusivity (MD), fractional anisotropy (FA), primary (λ1) and transverse eigenvalues (λ2, 3) were measured in region of interest (ROI) at the posterior limb of internal capsule. Pearson correlation analysis and two-way ANOVA were performed. Results None of the diffusion indices was correlated with TR (P>0.05) when SNR was high enough (SNR>35). FA was significantly higher and the MD and λ2, 3 were significantly lower at 3.0T than those at 1.5T (P<0.001). No significant difference of λ1 was found between the two field strengths (P>0.05). Conclusion Field strength may influence diffusion quantification, but not for TR, which should be considered in multi-center studies.
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