| 庞超楠,刘晓光,袁慧书.颈椎郎格罕细胞组织细胞增生症的CT征象分析[J].中国医学影像技术,2009,25(6):1072~1074 |
| 颈椎郎格罕细胞组织细胞增生症的CT征象分析 |
| CT findings of cervical Langerhans cell histiocytosis |
| 投稿时间：2008-11-12 修订日期：2009-02-23 |
| DOI： |
| 中文关键词: 颈椎 郎格罕细胞组织细胞增生症 体层摄影术,X线计算机 |
| 英文关键词:Cervical vertebra Langerhans cell histiocytosis Tomography, X-ray computed |
| 基金项目:国家自然科学基金(30840081)。 |
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| 中文摘要: |
| 目的 观察颈椎郎格罕细胞组织细胞增生症的CT表现及其演变过程。方法 回顾分析33例经病理证实的颈椎郎格罕细胞组织细胞增生症及其中14例随访病例的CT表现。结果 33例共34个病灶,病变以同时累及椎骨的前、后部结构最常见。全部病例均表现为不同程度的溶骨性骨质破坏,椎体有不同形态及程度的压缩,骨皮质不完整及软组织肿块形成。21个病灶有膨胀性改变,9个病灶骨皮质增厚,4个病灶周围骨质硬化,8个病灶有相邻椎骨的骨侵犯。随访病例CT表现为病灶范围缩小、骨密度增高,周围软组织肿块缩小或消失,病灶周围出现骨质硬化、骨皮质增厚,压缩椎体的高度有一定程度恢复。结论 颈椎郎格罕细胞组织细胞增生症的CT表现具有多样性,其表现与病变发展的不同时期有关,具有一定特征性,对该病的诊断具有较大帮助。 |
| 英文摘要: |
| Objective To observe the CT findings and evolution process of the cervical Langerhans cell histiocytosis (LCH). Methods The CT findings were retrospectively analyzed in 33 cases of LCH. All the cases were confirmed pathologically, and 14 cases were followed up. Results In all the 34 lesions of 33 cases, the lesions located mostly in both vertebral body and appendix. Osteolysis and cortical destruction, different degrees of vertebral compression and soft-tissue mass were found in all 34 lesions. Other changes such as expansion (21/34), cortical thickness (9/34) and peripheral osteosclerosis (4/34) could also be demonstrated in some lesions. Adjacent vertebrae were involved in 8 of 34 lesions. The CT findings of the follow-up cases included reduction of lesion range, increase of bone density, decrease or disappearance of soft-tissue mass, peripheral osteosclerosis, cortical bone thickness and vertebral height recovery in some degree. Conclusion The diversity of CT findings can be regarded as the characteristic features of the cervical LCH. The imaging manifestations are related to the different periods of the disease progress, and are helpful for the diagnosis of this disease. |
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