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李伟,樊卫.¹⁸F-FDG PET/CT食管异常代谢灶诊断食管恶性病变的价值[J].中国医学影像技术,2009,25(5):901~904

¹⁸F-FDG PET/CT食管异常代谢灶诊断食管恶性病变的价值

Value of esophageal abnormal metabolism lesions of ¹⁸F-FDG PET/CT for the clinical diagnosis of esophageal malignancy

投稿时间：2008-09-04 修订日期：2009-02-10

DOI：

中文关键词: 食管肿瘤氟脱氧葡萄糖诊断影像学

英文关键词:Esophageal neoplasms Fluorodeoxyglucose Diagnostic imaging

基金项目:

作者	单位	E-mail
李伟	中山大学肿瘤防治中心核医学科，广东广州 510060 华南肿瘤学国家重点实验室，广东广州 510060
樊卫	中山大学肿瘤防治中心核医学科，广东广州 510060 华南肿瘤学国家重点实验室，广东广州 510060	fanwei@mail.sysu.edu.cn

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中文摘要:

目的评价¹⁸F-FDG PET/CT发现食管异常代谢灶对临床诊断食管恶性病变的价值。方法 ¹⁸F-FDG PET/CT检查发现食管(包括贲门)异常代谢灶患者67例，按照PET/CT结果分为弱阳性组（16例）、一般阳性组（24例）与强阳性组（27例）。将三组病例的PET/CT结果与病理或临床随访结果进行对照。结果 PET/CT弱阳性组中恶性病变7例（43.75%），一般阳性组中恶性病变22例（91.67%），强阳性组中恶性病变26例（96.30%）。整体上三组之间差异存在统计学意义（χ²=18.732，P<0.05）。一般阳性组与强阳性组之间差异无统计学意义（χ²=0.011，P=0.916>0.017），弱阳性组与一般阳性组之间差异有统计学意义（χ²= 8.783，P=0.003<0.05），弱阳性组与强阳性组之间存在统计学差异（χ²=12.738，P<0.017）。结论 PET/CT一般阳性组与强阳性组的恶性病变发生率均很高，二者无显著差异；弱阳性组恶性病变发生率达43.75%，临床对此应予足够重视。

英文摘要:

Objective To estimate the value of ¹⁸F-FDG PET/CT in different groups' abnormal metabolism lesions of esophagus (including gastric cardia) for the clinical diagnosis of esophageal malignancy. Methods Sixty-seven patients with esophageal (including gastric cardia) abnormal metabolism lesions of ¹⁸F-FDG PET/CT were divided into 3 groups according to the results of PET/CT: weak positive group (16 cases), middle positive group (24 cases) and strong positive group (27 cases). With the contrast of PET/CT and pathology or clinical follow-up, chi-square test was performed to judge if there was statistical difference in each two groups among these three groups. Results Malignancies was diagnosed in 7 cases(43.75%) in weakly positive group, 22 cases (91.67%) in common positive group and 26 cases (96.30%) in strong positive group. There was statistical difference among three groups (χ²=18.732, P<0.05), but no statistical difference between strong positive group and common positive group (χ²=0.011, P=0.916>0.017). Statistical difference was found between weakly positive group and common positive group (χ²= 8.783, P=0.003<0.017) and between weakly positive group and strong positive group (χ²=12.738, P=0.000<0.017). Conclusion The incidence rates of malignancy are not noticeably different between common positive group and strong positive group. The incidence rate of malignancy was 43.75% in this study indicating that clinicians should watch out for patients of weakly positive group.

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