李新民,王霄英,郭雪梅,王鹤,蒋学祥.前列腺3D 1H-MRSI:体线圈与直肠内线圈谱线质量对照[J].中国医学影像技术,2009,25(5):848~852
前列腺3D 1H-MRSI:体线圈与直肠内线圈谱线质量对照
Three-dimensional 1H-magnetic resonance spectroscopic imaging of prostate gland: using body coil and endorectal coil
投稿时间:2008-12-03  修订日期:2009-02-08
DOI:
中文关键词:  前列腺  磁共振波谱
英文关键词:Prostate  Magnetic resonance spectroscopy
基金项目:首都医学发展科研基金(2007-2006)。
作者单位E-mail
李新民 北京大学第一医院医学影像科,北京 100034  
王霄英 北京大学第一医院医学影像科,北京 100034
北京大学前沿交叉学科研究院功能成像研究中心,北京 100034 
cjr.wangxiaoying@vip.163.com 
郭雪梅 北京大学第一医院医学影像科,北京 100034
北京大学前沿交叉学科研究院功能成像研究中心,北京 100034 
 
王鹤 北京大学第一医院医学影像科,北京 100034  
蒋学祥 北京大学第一医院医学影像科,北京 100034
北京大学前沿交叉学科研究院功能成像研究中心,北京 100034 
 
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中文摘要:
      目的 比较前列腺体线圈(BODY)与直肠内线圈(ERC)3D 1H-MRSI的谱线质量,探讨BODY MRS临床应用的可行性。方法 40例前列腺疾病患者,最终获得可测量的BODY与ERC MRS数据者30例。在MRS上将前列腺中央腺体和外周带左、右侧分为底部、中部及尖部,共12个兴趣区;对比BODY和ERC MRSI的各区对应体素的信噪比(SNR)、脂峰强度、(Cho+Cre)/Cit比值。结果 ①SNR:前列腺外周带的底部、中部及尖部左、右侧的SNR,BODY与ERC比较差异均有统计学意义(P均<0.05),均为SNRERC>SNRBODY;中央腺体底部左、右侧的SNR,BODY与ERC比较差异有统计学意义(P均<0.05),均为SNRBODY>SNRERC;②脂峰强度:前列腺外周带底部的左、右侧及尖部左侧脂峰强度两种线圈比较差异有统计学意义(P均<0.05),ERC>BODY;前列腺中央腺体底部左、右侧及中部左侧脂峰强度两种线圈比较差异有统计学意义(P均<0.05),均为ERC>BODY;③MRS各区体素(Cho+Cre)/Cit比值差异无统计学意义。 结论 前列腺BODY 3D 1H MRS总体谱线质量能够接受,虽然波谱的SNR略低于直肠内线圈,但其谱线受脂峰影响较小。
英文摘要:
      Objective To compare the quality of 3D 1H-MRSI of body coil (BODY) and endorectal coil (ERC) in prostate gland examination, and to discuss the clinical feasibility of BODY MRS. Methods Both BODY and ERC MRS were performed in 40 consecutive patients, and measurable MRS data was obtained in 30 patients. The right and left side of the peripheral and central zone of prostate were divided into bottom, middle and tip regions of interesting (ROI), respectively. Twelve ROIs were obtained in each case. The following parameters relating of MRS quality were compared, i.e. signal-to-noise ratio (SNR), lipid peak and ratio of (Cho+Cre)/Cit. Results ①The SNR in the peripheral zone of different individuals using ERC was statistically higher than that of using BODY MRS (P<0.05). The SNR in the central gland of bottom using ERC was statistically higher than that of using BODY MRS (P<0.05). ②The Lipid Peak in the peripheral zone of the bottom and the left of tip acquired using ERC was statistically higher than that of using BODY MRS (P<0.05). The Lipid Peak in the central zone of the bottom and the left of middle acquired using ERC was statistically higher than that of using BODY MRS (P<0.05). ③The mean ratios of (Cho+Cre)/Cit in the peripheral zone and central zone of different individuals acquired using both coils were not significantly different (P>0.05). Conclusion The MRS data can be reliably acquired using BODY MRSI, while the SNR and the Lipid Peak of BODY are inferior to those of ERC MRS.
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