| 谢耀钦,包尚联,陈国跃.肝脏影像的薄板样条弹性配准[J].中国医学影像技术,2009,25(3):499~503 |
| 肝脏影像的薄板样条弹性配准 |
| Thin plate spline deformable registration of liver images |
| 投稿时间：2008-11-27 修订日期：2008-12-23 |
| DOI： |
| 中文关键词: 动态适形调强放疗 影像导引的放射治疗 弹性配准 薄板样条 |
| 英文关键词:Four dimensional intensity modulated radiation therapy Image-guided radiation therapy Deformable registration Thin plate spline |
| 基金项目:国家自然科学基金(60672104),北京市自然科学基金(3073019),北京教委共建项目(JD100010607)。 |
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| 中文摘要: |
| 目的 在弹性配准中考虑肝脏周边解剖结构间运动的不连续性。方法 采用双薄板样条弹性配准方法,利用制定治疗计划过程中于参考影像中勾画的轮廓线信息对特征点进行分区。结果 对临床病例进行配准,沿人体上下方向偏移量绝对值的平均误差从配准前的11.25 mm降到配准后的1.80 mm,标准方差从2.60 mm降到1.39 mm。结论 该方法考虑了脏器间运动的不同模式,并且不需要在配准中对目标影像进行轮廓线勾画。 |
| 英文摘要: |
| Objective To take the discontinuous movements of anatomic structures around liver into account in deformable registration. Methods Bi-TPS (thin plate spline) deformable registration was proposed. The method partitioned the feature points according to the physician's segmentation of the template image during treatment planning. Results The average error and the standard deviation (SD) in modeling the absolute value of the displacement in the superior/inferior direction were reduced from (11.25±2.60)mm before registration to (1.80±1.39)mm after registration in a patient with liver tumor. Conclusion The proposed method can take the different motions of anatomic structures into consideration and allow segmented registration without delineating contours in the target images. |
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