| 张丽,胡道予,胡学梅,夏黎明,朱文珍,王承缘.MRS和MR-DTI对肝硬化诊断、分级效果的比较[J].中国医学影像技术,2009,25(3):459~461 |
| MRS和MR-DTI对肝硬化诊断、分级效果的比较 |
| Comparison of MRS and MR-DTI on clinical assessment in patients with liver cirrhosis |
| 投稿时间：2008-06-11 修订日期：2008-10-22 |
| DOI： |
| 中文关键词: 肝硬化 磁共振波普 磁共振弥散张量成像 ROC曲线 |
| 英文关键词:Liver cirrhosis Magnetic resonance spectropy MR-DTI ROC curve |
| 基金项目:湖北省科技攻关项目(2007AA301B41)。 |
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| 中文摘要: |
| 目的 测量并比较MRS及MR-DTI对肝硬化诊断、分级的效果。方法 分析87例MR-DTI、81例MRS受检者资料,结合临床诊断及Child分级资料,通过ROC曲线及界值进行比较分析。结果 独立指标FA、ADC、Cho、Glx的ROC曲线下面均大于0.5且P<0.05,其中ADC值的曲线下面积最大,平行联合实验表明MR-DTI 的ROC曲线下面积要稍高于MRS;ADC值在对照组、Child A、B、C各组之间存在明显的差异(P值分别为0.001、0.000、0.000),其他测量值在对照组和Child A组中的差异无统计学意义。结论 MRS和MR-DTI在肝硬化的诊断和分级方面均有较好的效果,MR-DTI效果更优。 |
| 英文摘要: |
| Objective To compare the value of magnetic resonance spectroscopy (MRS) and magnetic resonance-diffusion tensor imaging (MR-DTI) in diagnosing and staging of liver cirrhosis. Methods The MRI of 87 MR-DTI examinees and 81 MRS examinees were analyzed. The measured values were calculated and compared with receiver operating characteristic (ROC) curves. Results The areas under the ROC curves (AUC) of fractional anisotyopy (FA), average diffusion coefficient (ADC), choline (Cho) and glutamine and glutamane complex (Glx) were all larger than 0.5. The AUC between MRS and DTI were significantly different (DTI>MRS), and the ADC values were significantly different among control group, Child A group, Child B group and Child C group; other measured values were not significantly different between the control group and Child A group. Conclusion Both MRS and MR-DTI have good evaluation effect in liver cirrhosis. However, the effect of DTI is much better than that of MRS. |
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