| 骆志玲,郭涛,顾云,倪锐志,王钰,沈艳,陆永萍.超声心动图在心脏再同步化治疗室间间期优化中的应用[J].中国医学影像技术,2009,25(3):419~422 |
| 超声心动图在心脏再同步化治疗室间间期优化中的应用 |
| Interventricular delays optimization of cardiac resynchronization therapy: observation with echocardiography |
| 投稿时间：2008-07-21 修订日期：2008-10-06 |
| DOI： |
| 中文关键词: 心脏再同步化治疗 超声心动描记术 VV间期优化 即刻疗效 |
| 英文关键词:Cardiac resynchronization therapy Echocardiography VV delay optimization Immediate effect |
| 基金项目: |
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| 摘要点击次数: 2006 |
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| 中文摘要: |
| 目的 探讨超声心动图在心脏再同步化治疗(CRT)室间间期(VVD)优化中的价值。方法 7例CRT患者行VVD优化,比较不同VVD的超声心动图指标的即刻差异。结果 7例中左心室优先优于右心室优先和双室同步起搏:左心室优先时超声心动图测量的心功能指数(Tei指数)、左右心室射血前期延迟(PETd)、左心室壁12节段收缩达峰速时间标准差(TS-12-SD)、左心室收缩后收缩(PSS)减小,左心室收缩期压力上升速率(dp/dt)、主动脉流速时间积分(VTIAV)增大(P均＜0.05);左心室射血分数(EF)增高,但差异无统计学意义;双室同步起搏与右心室起搏的超声心动图各项指标均差异无统计学意义(P均＞0.05)。最优VVD分布在10~30 ms,但个体差异明显。结论 超声心动图指导下CRT患者VV间期优化可使CRT患者获得即刻血流动力学指标改善。 |
| 英文摘要: |
| Objective To explore the value of VV optimizing of cardiac resynchronization therapy (CRT) by echocardiography. Methods Seven in-patients with congestive heart failure receiving VV delays optimization were observed with echocardiography, and the immediate differences of echocardiographic parameters at different VV intervals were recorded. Results LV pre-activation was superior to simultaneous and RV pre-activation. Under such condition, Tei index, PETd, TS-12-Sd and PSS decreased, while dp/dt and VTIAV increased (P<0.05). There was no obvious difference between simultaneous pacing and RV pre-activation measured with echocardiography (P>0.05). LV pre-activation delay ranged from 10 ms to 30 ms, but there was individual variability. Conclusion Immediate improvement of hemodynamic is available in CRT patients undergoing optimization of VV delays under the supervision of echocardiograph. |
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