李洁,王小宜,倪军.神经梅毒的MRI表现[J].中国医学影像技术,2009,25(3):380~382
神经梅毒的MRI表现
MR image features of neurosyphilis
投稿时间:2008-07-10  修订日期:2008-12-24
DOI:
中文关键词:  神经梅毒  磁共振成像
英文关键词:Neurosyphilis  Magnetic resonance imaging
基金项目:
作者单位E-mail
李洁 中南大学湘雅医院放射科,湖南 长沙 410008  
王小宜 中南大学湘雅医院放射科,湖南 长沙 410008 cjr.wangxiaoyi@vip.163.com 
倪军 南华大学肿瘤研究所,湖南 衡阳 421001  
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中文摘要:
       目的 探讨神经梅毒的MR成像特点,提高对神经梅毒MRI表现的认识。方法 收集临床证实的13例神经梅毒患者进行回顾性分析。结果 MRI表现病变部位位于额叶(7例),顶叶(6例),颞叶(1例),基底节区(2例),脑桥(2例),小脑(3例),脊髓(2例),脑萎缩(11例),T1WI呈低信号、T2WI呈高信号。增强后脑膜型神经梅毒呈脑回样强化;脑膜血管性呈点状、片状不强化灶;树胶肿型见结节状不均匀强化,周围有大片不强化的水肿带;脊髓痨型呈片状、条状不强化灶等。结论 神经梅毒的MRI表现多样,早期诊断须综合分析影像学资料、实验室检查。
英文摘要:
      Objective To observe the imaging manifestations of neurosyphilis. Methods Clinical and imaging data of 13 patients with clinically proven neurosyphilis was collected and retrospectively analyzed. Results Lesions located in frontal lobe (n=7), parietasl lobe (n=6), temporal lobe (n=1), basal ganglia (n=2), the pontine (n=2), cerebellum (n=3) or in chorda spinalis (n=2), as multiple rounded T2 high signal intensity and T1 low signal intensity, with brain atrophy in 11 patients. After injection of Gd-DTPA, gyria-enhancment was detected in meanings neurosyphilis, punctiform and lamellar unenhancment was found in meningovascular neurosyphilis, while irregularly enhancing with extensive surrounding edema was noticed in cerebral gumma, and lamellar and strip unenhancment were depicted in myelophthisis. Conclusion Neurosyphilis has untypical imaging presentation. Comprehensively analysis of imaging data and laboratory examination is helpful to early diagnosis of neurosyphilis.
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