| 杨芳,吉民综述,顾宁.以纳米分子探针为基础的分子影像技术在肿瘤早期检测中的应用[J].中国医学影像技术,2009,25(2):316~318 |
| 以纳米分子探针为基础的分子影像技术在肿瘤早期检测中的应用 |
| Nanoparticles probe for targeted molecular imaging in early detection of cancer |
| 投稿时间：2008-07-02 修订日期：2008-11-04 |
| DOI： |
| 中文关键词: 纳米粒子 分子影像 探针 肿瘤 早期诊断 |
| 英文关键词:Nanoparticles Molecular imaging Probe Neoplasms Early diagnosis |
| 基金项目:国家重大科学研究计划(2006CB933206),国家自然科学基金(60371027, 50872021)。 |
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| 中文摘要: |
| 包含纳米材料、纳米器件以及纳米表征测量等的纳米技术,对生物、医学的进步产生了巨大影响。尤其利用纳米材料独特的颗粒及光学、电学等特性,结合现代医学影像技术,如光学成像、CT、PET/SPECT、MRI及超声成像(US)等,有可能在肿瘤发生初期进行早期特异性检测和有效的靶向治疗,使影像医学从对传统的解剖和生理功能的研究进展到分子水平成像,实现靶向分子成像,探索疾病的分子水平变化,在疾病早期做出明确诊断。 |
| 英文摘要: |
| Nowadays, nanotechnology, such as nano-materials, nano-devices and nano-characterization technology, has greatly influenced biological and medical development. Especially, the nanoparticles have unique size, optical and electronic characteristics. Combing nanoparticle-based molecular probe with the medical imaging technology, the cancer can be detected at very early stage by specific detection and effective targeted therapy will be performed accordingly. In this way, medical imaging changes from the study of conventional anatomy and physiology to molecular imaging, which makes targeted molecular therapy and early detection of tumor into reality. |
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