张艳,李俊来.相对造影参数在乳腺良恶性病灶鉴别诊断中的价值[J].中国医学影像技术,2009,25(1):97~99
相对造影参数在乳腺良恶性病灶鉴别诊断中的价值
Value of relative CEUS parameters in the differential diagnosis of breast lesions
投稿时间:2008-08-11  修订日期:2008-09-27
DOI:
中文关键词:  乳腺肿瘤  超声检查  造影剂
英文关键词:Breast neoplasms  Ultrasonography  Contrast media
基金项目:
作者单位E-mail
张艳 解放军总医院超声科,北京 100853  
李俊来 解放军总医院超声科,北京 100853 li_jl@yeah.net 
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中文摘要:
       目的 通过获取造影定量参数及计算相对造影参数评价其对乳腺病灶良恶性鉴别诊断的价值。方法 对54例经病理结果证实的乳腺病灶(良性31例,恶性23例)进行超声造影检查,使用ACQ软件对病灶及病灶旁组织增强感兴趣区绘制时间-强度曲线,测定超声造影参数,并计算相对造影参数。结果 以病灶周围腺体为对照,良性组时间-强度曲线多数(80.65%,25/31)为与腺体曲线接近型,或呈缓升速降型,峰值后移。恶性组时间-强度曲线多数(91.30%,21/23)呈速升缓降型,峰值前移。病灶相对开始增强时间、相对达峰时间及相对峰值强度在乳腺良恶性病灶之间比较差异均有统计学意义(P<0.05)。相对基准强度良恶性之间差异无明显统计学意义(P>0.05)。结论 研究乳腺病灶的造影参数应充分重视病灶周围腺体的增强情况,计算病灶与周围腺体造影参数的差值并结合时间-强度曲线形态特点进行良恶性对比分析更有意义。
英文摘要:
      Objective To study the value of parameters and relative parameters of contrast-enhanced ultrasound (CEUS) in the differential diagnosis of breast lesions. Methods A total of 54 patients with breast lesions (31 benign, 23 malignant) underwent CEUS. The time-intensity curves of lesions and surrounding tissues were drawn by software of ACQ, and then the parameters and calculation of the relative parameters of CEUS were obtained. Results The time-intensity curves of benign masses closed to those of surrounding tissues, or showed wash-in slowly and wash-out quickly, while of malignant masses showed wash-in quickly and wash-out slowly (P<0.05). The lesions'relative arrival time, time to peak and peak intensity were different between benign and malignant lesions (P<0.05), but no significant difference was detected in relative base intensity between benign and malignant lesions. Conclusion More attention should be paid to enhancement of surrounding tissues in the study of prameters of CEUS. The relative parameters of CEUS and the shapes of time-intensity curves may help to diagnose breast lesions.
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