| 刘庆先,夏爽,祁吉.中毒性脑病的影像学表现及DWI的价值[J].中国医学影像技术,2009,25(1):54~57 |
| 中毒性脑病的影像学表现及DWI的价值 |
| Imaging features of toxic encephalopathy and the values of DWI |
| 投稿时间：2008-07-15 修订日期：2008-10-09 |
| DOI： |
| 中文关键词: 神经毒性综合征 体层摄影术,X线计算机 磁共振成像 |
| 英文关键词: Neurotoxicity syndromes Tomography, X-ray computed Magnetic resonance imaging |
| 基金项目: |
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| 摘要点击次数: 2106 |
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| 中文摘要: |
| 目的 观察各种中毒性脑病的CT与MRI表现。方法 8例中毒性脑病患者,其中3例接受CT检查,4例接受MRI检查,1例接受CT和MR检查。结果 中毒性脑病主要累及脑白质,部分神经核团及灰质也可受累,MRI均见广泛脑白质长T1、长T2信号,弥散加权成像(DWI)呈高信号,CT表现为相应部位低密度,病变对称分布,无占位效应。有机溶剂中毒性脑病表现为广泛的大脑白质及神经核团长T1、长T2信号,DWI呈高信号,提示血管源性水肿;H2S中毒性脑病表现为大脑白质及部分神经核团多发长T1、长T2信号,DWI呈高信号,ADC值降低,40天后复查MRI病变范围较前缩小,DWI信号较前减低;有机磷及安定中毒性脑病均表现为弥漫性脑水肿,灰白质均受累。结论 CT和MRI能发现脑白质及神经核团的变性和坏死改变。与常规MRI相比,DWI能更敏感地反映病变。 |
| 英文摘要: |
| Objective To assess the CT and MR imaging of toxic encephalopathy. Methods Eight patients suffered from different toxic substance were studied, including 2 cases with solvents, 3 cases with hydrogen sulfide inhalation, 2 cases with organophosphate poisoning and 1 case with diazepam poisoning. Three of them underwent cranial CT examination , 4 underwent cranial MR examination. One of them underwent both CT and MR examination. Results Toxic encephalopathy mainly involved the white matter and some nucleus, and gray matter was also involved. CT and MR imaging had some common appearances. On CT, symmetrical low densities were observed in the white matter and nucleus. On MRI, these lesions showed long T1 and long T2 signal intensity and on DWI showed hyperintensity. The toxic encephalopathy MR imaging caused by chronic organic solvent inhalation revealed long T1 and long T2 white matter and nuclei changes, on DWI showed hyperintensity, and the value of ADC increased,which meant the edema was vesogenic edema. Conclusion CT and MRI can detect the leukoencephalopathy, the nuclei degeneration and necrosis of toxic encephalopathy. DWI is more sensitive to detect the abnormalities of the white matter than routine MRI. |
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