| 聂晶,孙跃民,张文娟,李晓春,林青.99mTc-MIBI/18F-FDG 双核素显像对冠心病患者存活心肌的评价[J].中国医学影像技术,2008,24(s1):199~201 |
| 99mTc-MIBI/18F-FDG 双核素显像对冠心病患者存活心肌的评价 |
| Evaluation of myocardial viability in patients with coronary heart disease using 99mTc-MIBI/18F-FDG myocardial tomography with dual isotope simultaneous acquisition |
| 投稿时间：2008-02-03 修订日期：2008-05-24 |
| DOI： |
| 中文关键词: 冠状动脉疾病 急性冠脉综合征 心肌梗死 双核素显像 |
| 英文关键词:Coronary disease Acute coronary syndrome Myocardial infarction Dual isotope simultaneous acquisition |
| 基金项目: |
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| 中文摘要: |
| 目的 应用99mTc-甲氧基异丁基异腈(MIBI)和18F-脱氧葡萄糖(FDG)双核素显像(DISA)比较直接经皮冠状动脉(简称冠脉)介入治疗(PCI)与择期PCI对急性心肌梗死(AMI)患者心肌存活性的影响以及不稳定性心绞痛(UA)患者心肌存活性。 方法 将63例冠心病患者分为3组:心肌梗死(MI)1组:行直接PCI的AMI患者21例;MI2组:行择期PCI的AMI患者20例;UA组:行PCI的UA患者22例;上述三组于PCI后1周 |
| 英文摘要: |
| Objective To evaluate the myocardial viability and cardiac function in patients with coronary heart disease after percutaneous coronary intervention (PCI) therapy using 99mTc-MIBI/18F-FDG myocardial tomography with dual isotope simultaneous acquisition (DISA). Methods A total of 63 patients with coronary heart disease underwent PCI therapy, including MI1 group (21 acute myocardial infarction patients who get primary PCI), MI2 group (20 acute myocardial infarction patients who get selective PCI) and UA group (22 unstable angina patients). 17 patients with normal coronary are involved in control group.During hospitalization myocardial viability and situation of myocardial effusion were assessed using DISA. Results The percentages myocardial segments of hypoperfusion and improved FDG uptake in primary PCI group were 21.7% (41/189) and 70.7% (29/41), while in selective PCI group were 34.3% (62/180) and 43.5% (27/62). In UA group the percentages were 21.2% (42/198) and 83% (35/42). There was significant difference between MI1 group and MI2 group, but no difference between MI1 group and UA group. Conclusion The study shows that primary PCI is more effetive than selective PCI in retrieving viable myocardium and protecting cardiac function after AMI. There exists inviable myocardium in patients with UA. |
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