李庆,寇卫红,刘悦,郑丽.经颅多普勒预测颅内大动脉狭窄与多血管事件关系研究[J].中国医学影像技术,2008,24(s1):52~54
经颅多普勒预测颅内大动脉狭窄与多血管事件关系研究
Study on transcranial Doppler ultrasound predicting relation of intracranial arterial stenosis and further vascular events
投稿时间:2008-02-18  修订日期:2008-07-28
DOI:
中文关键词:  颅内动脉狭窄  脑血管意外  超声检查,多普勒
英文关键词:Intracranial arterial stenosis  Cerebrovascular accident  Ultrasonography, Doppler
基金项目:
作者单位E-mail
李庆 石家庄市中医院功能科,河北 石家庄 050051 liqingliyang @126.com 
寇卫红 石家庄市中医院功能科,河北 石家庄 050051  
刘悦 石家庄市中医院功能科,河北 石家庄 050051  
郑丽 石家庄市中医院病案室,河北 石家庄 050051  
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中文摘要:
      目的 我们研究是否多血管事件能够帮助预测颅内大动脉狭窄的发生。 方法 用经颅多普勒,检测了131例住院患者的颅内大动脉血流速度,确定了每个病例狭窄动脉数量,并记录了多血管事件的发生情况。 结果 在131例中,66例无狭窄,65例至少有一支动脉狭窄。Logistic回归分析显示,预测短暂性脑缺血发作或脑中风的危险因素是舒张压的升高(OR=2.38, 95%CI 1.27到4.45, P=0.01)、存在大动脉狭窄(OR=2.15, 95%CI 0.
英文摘要:
      Objective We investigate whether further vascular events can help predict forms of intracranial large-artery stenosis. Methods Using transcranial Doppler, we measured blood velocity of intracranial large-artery in 131 patients who were hospitalized, we determined the number of stenosis artery and recorded baseline characteristics of further vascular events in consecutive patients. Results Among 131 consecutive patients, no stenosis arteries were found in 66 patients, 65 patients had at least 1 stenosis artery. Logistic regression analysis showed, hazardous predictors of transient ischemic attack and stroke were increasing of diastolic pressure (OR=2.38, 95%CI 1.27 to 4.45, P=0.01), large-artery stenosis (OR=2.15, 95%CI 0.96 to 4.84, P=0.06) and NIHSS score ≥2 (OR=18.83, 95%CI 4.06 to 87.28, P=0.001). Hazardous predictors of intracranial large-artery stenosis were diabetes (OR=2.78, 95%CI 1.20 to 6.46, P=0.02) and coronary syndromes (OR=2.63, 95%CI 1.13 to 6.15, P=0.03). Conclusion The risk of intracranial large-artery stenosis significantly increased in patients of diabetes and coronary syndromes. Patients with elevated diastolic pressure and intracranial large-artery stenosis easily suffered transient ischemic attack and stroke. Transcranial doppler ultrasound is an important investigation for study intracranial large-artery stenosis of patients with intracranial atherosclerotic disease.
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