张宇辉,陈明,刘怡,张波,苗爱雨,罗淮,RobertJ.Siegle.血管内超声评价冠心病患者的冠状动脉[J].中国医学影像技术,2008,24(12):1951~1954
血管内超声评价冠心病患者的冠状动脉
Intravascular ultrasound assessment on coronary artery of coronary heart diseases
投稿时间:2008-04-18  修订日期:2008-07-16
DOI:
中文关键词:  超声检查  冠状动脉疾病
英文关键词:Ultrasonography  Coronary artery disease
基金项目:
作者单位E-mail
张宇辉 同济大学附属东方医院心脏中心,上海 200120  
陈明 同济大学附属东方医院心脏中心,上海 200120 mingchen1283@vip.163.com 
刘怡 同济大学附属东方医院心脏中心,上海 200120  
张波 同济大学附属东方医院心脏中心,上海 200120  
苗爱雨 同济大学附属东方医院心脏中心,上海 200120  
罗淮 美国Cedars-Sinai医学中心,心脏无创伤检查实验室,洛杉矶 90048-0750  
RobertJ.Siegle 美国Cedars-Sinai医学中心,心脏无创伤检查实验室,洛杉矶 90048-0750  
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中文摘要:
       目的 报告应用血管内超声(IVUS)评估冠心病患者冠状动脉重构及斑块稳定性诊疗的体会。方法 使用血管内超声观察236例冠心病患者(经冠状动脉造影确诊),其中不稳定型心绞痛(UA)78例,稳定型心绞痛(SA)61例,急性心肌梗死(AMI)97例。结果 SA组以稳定的纤维斑块为主,UA和AMI组以不稳定的软斑为主;UA和AMI组的偏心指数明显高于SA组(P<0.05)。UA组和AMI组以正性重构为主。结论 IVUS能更准确观察冠状动脉内粥样斑块的特点,观察冠状动脉管腔的形态及狭窄的严重程度,对冠心病诊断具有独特的临床价值。
英文摘要:
      Objective To investigate the morphological features of atherosclerotic plaques and coronary artery remodeling by intravascular ultrasound (IVUS) in patients with stable angina (SA), unstable angina (UA) and acute myocardial infarction (AMI). Methods A total of 236 patients with chest pain who underwent diagnostic coronary angiography (CAG) and IVUS were enrolled and analyzed. The characteristics of the plaques and artery remodeling were evaluated by IVUS. Results Patients in SA group mainly showed stable and fibrous plaques, while UA and AMI patients mainly had unstable and soft lipid plaques. Eccentric index (EI) was higher in UA and AMI patients than in SA patients (P<0.05). Patients in UA and AMI groups were prone to positive remodeling. Conclusion IVUS is an accurate tool in identifying the lumen morphology, the plaque characteristics and the stenostic severity, providing unique clinical value on the diagnosis of coronary heart diseases.
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