| 金龙,高健,陈雷,范岳峰,杜湘珂.应用自膨式金属支架姑息治疗无法手术的恶性梗阻性黄疸[J].中国医学影像技术,2008,24(11):1825~1828 |
| 应用自膨式金属支架姑息治疗无法手术的恶性梗阻性黄疸 |
| Palliative treatment for obstructive jaundice caused by unresectable malignancies by percutaneous transhepatic insertion of self-expandable metallic stents |
| 投稿时间：2008-09-10 修订日期：2008-09-22 |
| DOI： |
| 中文关键词: 支架 黄疸 |
| 英文关键词:Stents Jaundice |
| 基金项目: |
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| 中文摘要: |
| 目的 评价自膨式金属支架植入成形术治疗无法手术的恶性梗阻性黄疸及临床疗效。方法 对105例无法手术治疗的恶性梗阻性黄疸患者行胆道内支架成形术,术后随访3~755天,观察患者的临床症状改善情况及支架通畅情况。结果 共植入支架129枚,初次治疗的技术成功率为94.3%,78%患者术后达到临床显效的标准。术后30天患者死亡率为7.6％(8/105),死因均与介入操作无关。术后患者的中位生存期为189天,支架中位通畅时间为246天。术后3、6个月的支架通畅率分别为92.1％和64.5％。结论 自膨式金属支架植入术是姑息治疗恶性梗阻性黄疸的有效方法,准确判断无法从胆道支架成形术中获益患者将有助于改善支架成形术后的远期疗效。 |
| 英文摘要: |
| Objective To determine the technical feasibility and clinical efficacy of self-expandable metallic stents for palliation of obstructive jaundice caused by unresectable malignancies. Methods A total of 105 patients with unresectable malignant tumors involving the bile duct who presented with obstructive jaundice underwent transhepatic implantation of self-expandable metallic stents. The follow-up period of the patients was 3-755 days. Technical and clinical success, adverse events, patient survival, and duration of stent patency were analyzed. Results Percutaneous biliary stenting was performed on 105 malignant biliary obstructive patients with 129 self-expandable metallic stents. Technical successful rate was 94.3％, and clinical success rate was 78%. Thirty-day mortality after stenting was 7.6%, not procedure-related. Median survival time and stent patency of all patients were 189 days and 246 days. Primary patency rates were 92.1% and 64.5% at 3 and 6 months, respectively. Conclusion Self-expandable metal wall stenting for malignant obstructive jaundice provides good palliation with low, procedure-related morbidity and mortality in the long term. Further investigation to identify the subgroup of patients in whom stenting has no beneficial effect would be required. |
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