| 司丽芳,翟仁友,马展鸿.心率对64层螺旋CT冠状动脉造影诊断准确性的影响[J].中国医学影像技术,2008,24(11):1753~1756 |
| 心率对64层螺旋CT冠状动脉造影诊断准确性的影响 |
| Impact of heart rate on diagnostic accuracy of 64-slice spiral computed tomography coronary angiography |
| 投稿时间：2007-12-06 修订日期：2008-09-03 |
| DOI： |
| 中文关键词: 体层摄影术,X线计算机 冠状血管造影术 冠状动脉病变 |
| 英文关键词:Tomography, X-ray computed Coronary angiography Coronary disease |
| 基金项目: |
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| 摘要点击次数: 1986 |
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| 中文摘要: |
| 目的 评价心率对64层螺旋CT诊断冠状动脉狭窄准确性的影响。方法 对148例临床怀疑或确诊为冠心病的患者进行64层螺旋CT冠状动脉造影(CTCA)检查,将结果与传统冠状动脉造影(CCA)结果进行对照。入选患者按照心率不同分为3组:第一组为心率≤65次/分,第二组心率为66~75次/分,第三组为心率＞75次/分。结果 64层螺旋CT诊断冠状动脉狭窄≥50%的敏感性为89.75%,特异性为98.63%,阳性预测值为92.33%,阴性预测值为98.12%;诊断冠状动脉狭窄≥75%的敏感性为90.22%,特异性为99.21%,阳性预测值91.71%,阴性预测值99.05%。在不同心率组中,第一组诊断狭窄≥50%的敏感性为94.55%,特异性为98.80%,阳性预测值为95.50%,阴性预测值为98.54%。第二组诊断≥50%狭窄的敏感性为90.48%,特异性为98.43%,阳性预测值为87.69%,阴性预测值为98.82%。第三组诊断≥50%狭窄的敏感性为71.93%,特异性为95.91%,阳性预测值为67.21%,阴性预测值为96.70%。结论 64层螺旋CT对心率较慢的患者有较高的准确性,可作为临床无创筛查冠心病的有效手段。 |
| 英文摘要: |
| Objective To evaluate the impact of heart rate on the diagnostic accuracy of coronary angiography by 64-slice spiral computed tomography. Methods A total of 148 patients with suspected or diagnosed coronary artery disease underwent 64-slice computed tomography coronary angiography (CTCA), and the diagnostic outcome was compared with that of conventional coronary angiography (CCA). Patients were classified according to the heart rate into three groups: group I, ≤65 bpm; group II, 66—75 bpm; group III, >75 bpm. Results Accounting for all segments, including lesions in non-assessable segments as false negatives, the sensitivity (SE), specificity (SP), positive predictive value (PPV) and negative predictive value (NPV) was 89.75%, 98.63%, 92.33% and 98.12%, respectively, for detecting stenoses ≥50%, and 90.22%, 99.21%, 91.71%, 99.05%, respectively, for stenoses ≥75%. The SE, SP, PPV and NPV for detecting stenoses≥50% was 94.55%, 98.80%, 95.50% and 98.54% in group I, 90.48%, 98.43%, 87.69% and 98.82% in group II, and 71.93%, 95.91%, 67.21% and 96.70% in group III. Conclusion 64-slice spiral computed tomography can be used as a noninvasive assessment method of significant coronary artery stenoses. |
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