| 刘圣华,储成凤,杨明,刘斌,魏松宇.fMRI评价正常老年人腕关节被动运动下脑激活区[J].中国医学影像技术,2008,24(11):1693~1696 |
| fMRI评价正常老年人腕关节被动运动下脑激活区 |
| Functional magnetic resonance imaging with passive wrist movements in healthy elder people |
| 投稿时间：2008-03-21 修订日期：2008-07-30 |
| DOI： |
| 中文关键词: 磁共振成像 被动运动 腕 |
| 英文关键词:Magnetic resonance imaging Passive movement Wrist |
| 基金项目:东南大学科技基金资助(KJ0790300);部分受973项目资助(2007CD512303)。 |
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| 中文摘要: |
| 目的 用功能磁共振技术观察正常老年人双侧腕关节被动运动时脑区激活情况。方法 对30例正常的右利手老年受试者分别进行双侧腕关节被动运动的功能MR扫描,采用SPM2软件进行数据分析和脑功能区定位。结果 利手(右手)运动主要激活对侧感觉运动皮质、运动前区,双侧辅助运动区、后顶叶及同侧小脑;非利手运动时除激活上述脑区外,还激活了同侧运动感觉区和对侧小脑,且对侧运动前区、双侧辅助运动区和同侧小脑的激活体积明显大于利手腕关节运动。结论 被动运动依赖于大脑皮质和小脑等许多与运动相关的脑功能区的参与;与利手腕关节运动相比,非利手腕关节运动更依赖于对侧PMC、双侧SMA和同侧小脑等运动区。 |
| 英文摘要: |
| Objective To explore the similarities and differences between dominant and subdominant wrist movement in healthy elder people with functional magnetic resonance imaging. Methods Thirty right-handed healthy elder subjects were scanned while they were performing the passive movement tasks with their right and left wrists, and SPM2 was adopted to process the fMRI data and to localize the functional areas. Results Voluntary movements of the right dominant hand mainly activated contralateral sensorimotor cortex, contralateral premotor area (PMC), bilateral supplementary motor area (SMA), bilateral posterior parietal cortex, and ipsilateral cerebellum, whereas movements of the left/subdominant hand additionally elicited activation in ipsilateral sensorimotor cortex, contralateral cerebellum. Moreover, activation volumes in SMA, contralateral premotor area and ipsilateral cerebellum during movements of the subdominant hand were significantly larger than those during movements of the dominant hand. Conclusion A large set of structures in the cerebral cortex and cerebellum was involved in passive movements. Movements of the subdominant hand were more dependent on higher control areas, such as SMA, PMC and ipsilateral cerebellum comparing to movements of the dominant hand. |
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