杨维竹,江娜,黄宁,黄兢姚,郑曲彬,申权.经导管肝动脉化疗栓塞联合经皮微波凝固治疗小肝癌[J].中国医学影像技术,2008,24(10):1647~1649 |
经导管肝动脉化疗栓塞联合经皮微波凝固治疗小肝癌 |
Transcatheter arterial chemoembolization combining with percutaneous microwave coagulation therapy for small hepatocellular carcinoma |
投稿时间:2008-03-06 修订日期:2008-07-25 |
DOI: |
中文关键词: 癌,肝细胞 经肝动脉化疗栓塞 微波凝固治疗 |
英文关键词:Carcinoma, hepatocellular Transcatheter arterial chemoembolization Microwave coagulation therapy |
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中文摘要: |
目的 评价经导管肝动脉化疗栓塞术(TACE)联合微波凝固治疗小肝癌的疗效。 方法 35例肝癌患者(41个病灶,直径≤3 cm)接受TACE,1~3周后在CT引导下行微波凝固术治疗。 结果 通过活检及CT增强扫描,显示41个病灶完全性坏死,其中34个病灶伴有周边正常肝实质约3~5 mm完整环状坏死,7个病灶周边正常肝实质环状坏死不完整。25例AFP升高,治疗后10天内降至正常水平。随访6~31个月,1例于不同的肝段见复发病灶,另1例原病灶附近复发。随访期内患者均存活。 结论 肝动脉化疗栓塞术联合微波消融术治疗小肝癌,疗效好、安全、无严重并发症,值得进一步研究。 |
英文摘要: |
Objective To assess the efficacy of transcatheter arterial chemoembolization (TACE) combining with percutaneous microwave coagulation therapy (PMCT) in the treatment of small hepatocellular carcinoma (HCC). Methods Thirty-five HCC patients with 41 nodules (≤3 cm in diameter) were treated with TACE and CT-guided PMCT after 1-3 weeks. Results Complete necrosis of the tumor and the surrounding noncancerous area measuring 3-5 mm was obtained in 34 nodules, and incomplete necrosis of the surrounding parenchyma was observed in 7 nodules. Serum AFP level returned to normal 10 days after treatment in 25 patients who originally had a high serum AFP level. All patients remained alive during the 6-31 months follow-up period. Tumor recurrence was found in 2 patients, one in the different subsegment, the other in the near original target lesion. Conclusion TACE combining with percutaneous microwave coagulation therapy is a safe and effective treatment without severe complications. Further study should be recommended. |
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