高立,梁碧玲,张赟,钟镜联,叶瑞心.兔坐骨神经背景信号抑制扩散加权成像[J].中国医学影像技术,2008,24(10):1530~1533
兔坐骨神经背景信号抑制扩散加权成像
Diffusion weighted whole body imaging with background signal suppression (DWIBS) in peripheral nerve: animal experiment study
投稿时间:2008-04-18  修订日期:2008-07-24
DOI:
中文关键词:  坐骨神经  磁共振成像  扩散加权成像
英文关键词:Sciatic nerve  Magnetic resonance imaging  Diffusion-weighted imaging
基金项目:
作者单位E-mail
高立 深圳市龙岗中心医院放射科,广东 深圳 518116  
梁碧玲 中山大学附属第二医院放射科,广东 广州 510120 liangbl@163.net 
张赟 中山大学肿瘤防治中心放射科,广东 广州 510060  
钟镜联 中山大学附属第二医院放射科,广东 广州 510120  
叶瑞心 中山大学附属第二医院放射科,广东 广州 510120  
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中文摘要:
      目的 探讨DWIBS周围神经成像扫描参数的优化方案。方法 对5只健康新西兰白兔行坐骨神经冠状位MRN成像,评价不同参数组合DWIBS序列及T2WI/SPIR图像兔坐骨神经的显示效果以及图像信号噪声比(SNR)与对比噪声比(CNR)。制作兔坐骨神经组织切片。 结果 T2WI/SPIR图像和b值=200 s/mm2、层厚=2 mm的DWIBS序列兔坐骨神经成像效果较好。T2WI/SPIR图像SNR和CNR最高。DWIBS中,以b值=200 s/mm2、层厚=1.5 mm序列SNR、CNR最高。 结论 采用适当b值(200 s/mm2)和薄层扫描(1.5 mm)能够获得较好的兔坐骨神经DWIBS图像。
英文摘要:
      Objective To discuss DWIBS imaging protocols of peripheral nerve imaging. Methods MRN imaging of each sciatic nerve were obtained coronally in 5 adult New Zealand white rabbits. All images of rabbit sciatic nerve in DWIBS and T2WI/SPIR were observed, and the imaging qualities were evaluated by measurement the signal intensity of middle segment of sciatic nerve (SN), muscle (SM) and background (SD), also calculating signal-noise ratio (SNR) and contrast-noise ratio (CNR) of each sequence. Results The rabbit sciatic nerve was showed with high signal, especially on DWIBS (with b value=200 s/mm2, slice thickness=2 mm) and T2WI/SPIR. Among all images, T2WI/SPIR got the highest SNR and CNR. SNR and CNR of DWIBS with b value=200 s/mm2, slice thickness=2 mm was higher than those of other DWIBS sequences. Conclusion Preferable rabbit sciatic nerve DWIBS could be obtained with higher SNR and CNR by adopting b value(200 s/mm2) and smaller slice thickness. Histopathologic factors impacted DWIBS neuroimaging.
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