| 过哲,张晶,梁伟,李晓松,张薇,刘薇,程晓光.骨巨细胞瘤的动态增强MRI与1H-MR波谱研究[J].中国医学影像技术,2008,24(10):1490~1492 |
| 骨巨细胞瘤的动态增强MRI与1H-MR波谱研究 |
| Study of DCE MRI and 1H-MRS of giant cell tumor of bone |
| 投稿时间：2008-07-29 修订日期：2008-09-10 |
| DOI： |
| 中文关键词: 骨巨细胞瘤 磁共振成像 胆碱 |
| 英文关键词:Giant cell tumor of bone Megnetic resonance imaging Choline |
| 基金项目:首都医学发展科研基金(2005-3033)。 |
| 作者 | 单位 | E-mail | | 过哲 | 北京大学第四临床医学院,北京积水潭医院放射科,北京 100035 | xiao65@263.net | | 张晶 | 北京大学第四临床医学院,北京积水潭医院放射科,北京 100035 | | | 梁伟 | 北京大学第四临床医学院,北京积水潭医院放射科,北京 100035 | | | 李晓松 | 北京大学第四临床医学院,北京积水潭医院放射科,北京 100035 | | | 张薇 | 北京大学第四临床医学院,北京积水潭医院放射科,北京 100035 | | | 刘薇 | 北京大学第四临床医学院,北京积水潭医院放射科,北京 100035 | | | 程晓光 | 北京大学第四临床医学院,北京积水潭医院放射科,北京 100035 | |
|
| 摘要点击次数: 2552 |
| 全文下载次数: 1052 |
| 中文摘要: |
| 目的 探讨骨巨细胞瘤的动态增强MRI及MR氢质子波谱的特点及其在骨巨细胞瘤诊断中的作用。 方法 采用3D fast SPGR序列对21例病理证实的骨巨细胞瘤进行动态增强扫描,并采用点分辨波谱序列(PRESS)对其中12例进行单体素MR氢质子波谱扫描,分别经过工作站处理,得到动态增强扫描时间-信号强度曲线(TIC)及MR氢质子波谱谱线。以手术病理为标准,对骨巨细胞瘤的动态增强扫描时间-信号强度曲线及MR氢质子波谱的特点进行分析。 结果 21例骨巨细胞瘤的TIC曲线中,19例为Ⅰ型曲线,2例为Ⅱ型曲线;12例MR氢质子波谱的谱线中,9例具有诊断价值,其中有2例出现明显的胆碱峰。 结论 骨巨细胞瘤的TIC曲线表现为速升下降型,1H-MRS谱线缺乏胆碱峰或胆碱峰矮小。 |
| 英文摘要: |
| Objective To investigate the characteristic of dynamic contrast enhancement MRI scan and 1H-MR spectroscopy of giant cell tumor (GCT) of bone. Methods MRI was performed with 1.5T MR scanner . Twenty-one patients were examined with a three-dimensional fast SPGR dynamic MR imaging sequence. Singlevoxel 1H-MR spectroscopy was performed in 12 of the 21 patients with point-resolved spectroscopic sequence (PRESS). The acquired images were post-processed, then time-intensity curves and 1H-MR spectroscopic spectra of the GCT were obtained. Taking pathological diagnosis as gold standard, the types of time-intensity curves and 1H-MR spectroscopic spectra were evaluated. Results Nineteen cases showed type Ⅰ curve; only 2 cases showed type Ⅱ curves. Nine of the 12 1H-MR spectroscopy spectra had diagnostic value, and only 2 of them had noticeable choline peaks. Conclusion GCT shows type Ⅰ TIC curve, and has no noticeable or only have very small choline peak in 1H-MR spectroscopy spectra. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
