| 于德新,马祥兴,王茜,王青,崔凤玉,李笃民.双源CT显示老年退行性主动脉瓣病变与左心结构相关性研究[J].中国医学影像技术,2008,24(9):1326~1329 |
| 双源CT显示老年退行性主动脉瓣病变与左心结构相关性研究 |
| Study on the correlation between senile aortic valve diseasesand left heart structure with dual-source CT |
| 投稿时间：2008-05-20 修订日期：2008-08-21 |
| DOI： |
| 中文关键词: 主动脉瓣 钙化 体层摄影术,X线计算机 |
| 英文关键词:Aortic valve Calcification Tomography, X-ray computed |
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| 中文摘要: |
| 目的 利用双源CT检测老年退行性主动脉瓣病变及其导致的左心结构的改变。方法 选择双源CT冠状动脉成像显示的单纯主动脉瓣病变患者63例及正常对照组78例。根据图像测量和计算左心房、左心室壁的厚度、相对厚度及相对容积,左心房、左心室腔的大小,主动脉根部和近段的管径及两者之间的比值(主动脉比)。当钙化位于瓣膜的边缘、中央或两处均存在时分别定为1、2、3型,同时计算瓣膜钙化的面积及积分值。分析主动脉瓣钙化及其分级对于各测量值的影响。结果 63例主动脉瓣钙化者中,同时合并瓣膜肥厚者7例。1、2、3型钙化的病例数分别为30.16%(19/63)、39.68%(25/63)、30.16%(19/63);钙化位于右、左、后半月瓣或累计两个瓣膜以上分别为9.52%(6/63)、20.63%(13/63)、33.33%(21/63)、36.51%(23/63);在主动脉瓣钙化组和正常对照组之间,左心房壁厚度及相对容积、主动脉近段直径及主动脉比具有统计学差异(P<0.05);当钙化位于瓣膜边缘、中央或两处都存在时,室间隔厚度也存在统计学差异(P=0.024, F=3.193);主动脉根部及近段直径均与瓣膜钙化面积、钙化积分呈正相关关系(P<0.05)。但主动脉瓣肥厚未引起左心结构的改变。结论 双源CT可用于显示和评估老年退行性主动脉瓣病变及其导致的左心结构变化。 |
| 英文摘要: |
| Objective To detect the senile degenerative aortic valve diseases and the following changes of left heart using dual source CT. Methods Some senile cases who underwent dual source CT coronary artery angiography were selected and divided into aortic valve disease group (63 cases) and normal control group (78 cases). The thickness, relative thickness and volume, and lumen dimension of left atrium and ventricle, and the diameter of aortic root and proximal aorta and the aortic ratio of both diameters above were accessed at a workstation. Ⅰ-Ⅲ grades were defined when the calcification at periphery, center or both of the aortic valve respectively. Meanwhile the area and score of the calcification were also calculated automatically. The relationship between the aortic valve disease and the parameters of left heart measured above were analyzed. Results Sixty-three patients had aortic valve calcification in which 7 cases were identified with valve thickening. The cases with Ⅰ-Ⅲ grade calcification were 30.16% (19/63), 39.68% (25/63) and 30.16% (19/63). There were statistical differences in wall thickness and relative volume of left atrium, the diameter of proximal aorta, and the aortic ratio between pure aortic valve disease group and control group (P<0.05), and so was the difference in thickness of interventricular septum among three grades (P=0.024, F=3.193)). The positive correlations were gotten between the diameter of aortic root or proximal aorta and the area or scores of calcification (P<0.05). The aortic valve thickening did not cause the changes of the left heart structure in this study. Conclusion Dual source CT may be used to depict and evaluate the senile aortic valve diseases and the following left heart remolding. |
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