| 周宁,段云友,王勇,熊华强,王宇.孕期不同剂量彩色多普勒超声重复辐照对仔鼠自发活动的影响[J].中国医学影像技术,2008,24(8):1186~1188 |
| 孕期不同剂量彩色多普勒超声重复辐照对仔鼠自发活动的影响 |
| The effect of color Doppler ultrasound during different durations of pregnancy on offsprings’ locomotion activity |
| 投稿时间：2008-03-07 修订日期：2008-05-05 |
| DOI： |
| 中文关键词: 超声检查,多普勒,彩色 大鼠 开场实验 自发活动 |
| 英文关键词:Ultrasonography, Doppler, color Rats Open field test Locomotion activity |
| 基金项目:国家自然科学基金资助项目(30571966)。 |
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| 中文摘要: |
| 目的 观察孕期给予不同剂量彩超重复辐照后对仔鼠自发活动的影响。 方法 妊娠SD大鼠30只,随机分为对照组、重复照射10 min组、重复照射20 min组3组。在妊娠第6、12、18天分别给予0 min,10 min,20 min的(3.0 MHz,MI=1.6,Tis=1.8)超声辐照。生后90天通过开场实验观察其自发活动,评价其神经精神变化、进入开阔环境后的各种行为。 结果 与对照组相比,辐射10 min,20 min组仔鼠的活动总路程、活动度、中央区时间、中央区路程以及平均运动速度均无明显差异(P>0.05)。 结论 孕期诊断剂量彩超重复照射对仔鼠的自发活动不产生明显影响。 |
| 英文摘要: |
| Objective To investigate whether the Doppler ultrasound with different dose during different durations of pregnancy could have an effect on offspring' locomotion activity. Methods Thirty pregnant SD rats were randomly divided into three groups according to the exposure time:control group (0 min group), 10 min group, 20 min group. The rats were exposed to continuous ultrasound (3.0 MHz, MI=1.6, Tis=1.8) on 6th, 12th, and 18th days of gestation. In each group neonatal rasts were selected to open field test for locomotion activity at ninety days old. Results To the total distance,average velocity, activity, central distance and central time, there were no differences between the 10 min group, 20 min group and the control group (P>0.05). Conclusion Color Doppler ultrasound during different durations of pregnancy does not have any effect on offspring' locomotion activity. |
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