周琦,姜珏,刘百灵,雷小莹.超声造影在鉴别诊断腹部良恶性占位病变中的应用价值[J].中国医学影像技术,2008,24(7):1080~1082
超声造影在鉴别诊断腹部良恶性占位病变中的应用价值
Study of contrast-enhanced ultrasound in diagnosis of abdominal lesions
投稿时间:2008-02-04  修订日期:2008-06-01
DOI:
中文关键词:  超声检查,介入性  肝肿瘤  胆囊肿瘤  胰腺肿瘤
英文关键词:Ultrasonography, interventional  Liver neoplasms  Gallbladder neoplasms  Pancreatic neoplasms
基金项目:
作者单位E-mail
周琦 西安交通大学医学院第二附属医院超声研究室,陕西 西安 710004 zhouqi1998@yahoo.com.cn 
姜珏 西安交通大学医学院第二附属医院超声研究室,陕西 西安 710004  
刘百灵 西安交通大学医学院第二附属医院超声研究室,陕西 西安 710004  
雷小莹 西安交通大学医学院第二附属医院超声研究室,陕西 西安 710004  
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中文摘要:
      目的 探讨实时超声造影对腹部良恶性占位病变的鉴别诊断价值。 方法 对250例腹腔脏器占位性病变进行实时超声造影研究,其中包括肝脏良恶性肿瘤196例,胆囊癌及胆囊良性病变39例,胰腺良恶性病变15例, 所有病例均经过手术或其他影像学检查方法证实。 结果 造影剂SonoVue 2.4 ml静脉注射后,肝癌动脉相表现为整体快速增强,并在门脉相快速消退,在实质相显示为低回声;血管瘤呈周围向心性环状或结节状增强,门脉相及实质相进一步增强,持续较长时间;局灶性结节增生表现为中央扩散型快速整体增强,部分病例显示为车轮状;肝硬化增生结节的造影增强特征与肝实质一致;胆囊癌快速不均匀增强,胆囊壁连续性中断,胆囊良性病变及慢性胆囊炎胆囊壁连续;胰腺癌造影剂快速进入,消退时间早于胰腺实质,胰腺炎性肿块造影后回声与胰腺一致,或造影剂不进入。 结论 实时超声造影能显示肿瘤内微小血管的血流灌注情况,对腹部良恶性占位病变的定性诊断具有重要的意义。
英文摘要:
      Objective To evaluate the value of real-time contrast enhanced ultrasound in discrimination benign from malignant tumors of abdominal occupying lesions. Methods Totally 250 patients with abdominal occupying lesions were examined by contrast enhanced ultrasound, including 196 cases of tumors of the liver, 39 cases of lesions of gallbladders, 15 cases of lesions of pancreas. All cases were confirmed by histopathology or other image methods. Results After injection of SonoVue 2.4 ml, hepatocellular carcinomas showed a typical hypervascular pattern in the arterial phase and rapid wash-out in the portal phase. A peripheral and centripetal enhanced pattern was mostly shown in hemangiomas, high enhancement in the later phase. A pattern of a radial centrifugal enhanced in the very early arterial phase and a central stellate fibrous scar in portal phase was observed in FNHs. A pattern of enhancement similar to the surrounding parenchyma was observed in regenerative nodule. Quick and uneven enhancement was seen in gallbladder carcinoma, the wall of the gallbladder is interrupted by the mass. While the wall of the gallbladder is uninterrupted in cholecystitis and benign tumor of gallbladder. Fast and high enhancement in the pancreatic cancers, and wash-out time was significantly faster than normal pancreatic tissue. No enhancement or consistent with normal pancreatic tissue in inflammatory mass of pancreas. Conclusion Contrast enhanced ultrasound can show microvascular organization and parenchymal perfusion, it is very useful for diagnosing abdominal occupying lesions.
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