| 张泉,张云亭,冯凯琳,张敬,李威,张权.颞叶癫痫患者的颞干MR扩散张量成像研究[J].中国医学影像技术,2008,24(6):866~868 |
| 颞叶癫痫患者的颞干MR扩散张量成像研究 |
| Study of diffusion tensor imaging on temporal stem in patients with temporal lobe epilepsy |
| 投稿时间：2008-01-17 修订日期：2008-04-07 |
| DOI： |
| 中文关键词: 癫痫,颞叶 磁共振成像 颞干 |
| 英文关键词:Epilepsy, temporal Lobe Magnetic resonance imaging Temporal stem |
| 基金项目: |
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| 摘要点击次数: 2514 |
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| 中文摘要: |
| 目的 探讨颞叶癫痫(TLE)患者颞干扩散张量成像(DTI)参数的变化特点,并评价颞干DTI测量在TLE病灶定侧诊断中的辅助价值。方法 对临床诊断的42例发作间期TLE患者和32例正常志愿者行常规MRI和DTI检查,定量测量双侧颞干的平均扩散系数(DCavg)、部分各向异性(FA)、1-容积比(1-VR)和相对各向异性(RA)值并进行统计。结果 正常人双侧颞干之间的颞干DTI参数(DCavg、FA、1-VR和RA)均无显著性差异。TLE患者患侧颞干DCavg高于对侧颞干及正常人,而对侧颞干DCavg与正常人无显著性差异;患侧、对侧、正常人三组间FA、1-VR和RA存在显著性差异(患侧＜对侧＜正常人,P＜0.001)。发作间期患者的颞干DTI参数值对TLE的定侧诊断准确率为71.4%(30/42)。结论 TLE患者的颞干扩散运动变化有助于TLE的定侧诊断和对TLE继发白质损伤的认识。 |
| 英文摘要: |
| Objective To reveal the changing features of parameters of diffusion tensor imaging (DTI) and to study the value of DTI measurements in temporal stem to lateralize the epileptogenic lesion in patients with temporal lobe epilepsy (TLE). Methods Forty-two interictal patients of TLE and 32 healthy volunteers received conventional and DTI scanning. The DCavg, FA, 1-VR and RA of bilateral temporal stems were measured respectively and the data underwent post-processing. Results There were no significant differences of DCavg, FA, 1-VR and RA between right and left temporal stems in the control. The DCavg in ipsilateral side was higher than contralateral side and control group, but no significant difference of DCavg existed between contralateral side and control group. The FA, 1-VR, RA in temporal stem had significant differences among the three groups (ipsilateral side ＜ contralateral side ＜ control group, P＜0.001). The overall correct lateralization rate of interictal DTI parameters in temporal stem was 71.4% (30/42). Conclusion Diffusion changes in the temporal stem are helpful for understanding white matter injury in TLE and lateralizing the epileptogenic lesion. |
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