| 武志芳,程艳,张万春,刘建中,李险峰,胡光,王进.99mTc-N-NOET运动MPI对可疑或确诊冠心病患者的预后评估价值[J].中国医学影像技术,2008,24(5):777~780 |
| 99mTc-N-NOET运动MPI对可疑或确诊冠心病患者的预后评估价值 |
| Prognostic value of 99mTc-N-NOET SPECT exercise myocardial imaging in patients with suspected or diagnosed coronary artery disease |
| 投稿时间：2008-01-20 修订日期：2008-04-02 |
| DOI： |
| 中文关键词: 99mTc-N-NOET 心肺比值 冠状动脉疾病 |
| 英文关键词:99mTc-N-NOET Heart-lung ratio Coronary disease |
| 基金项目: |
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| 中文摘要: |
| 目的 99mTc-N-NOET 心肌灌注显像(MPI)对可疑或确诊冠心病(CAD)患者的预后评估价值。方法 111 例患者行 99mTc-N-NOET 运动和延迟门控MPI(GMPI),随后随访是否发生心脏事件(CE)。结果 平均随访(33.47±7.69)个月,10 例发生CE,单因素和多因素逐步 Logistic 回归分析结果显示,预测CE 发生最有价值的危险因素包括异常心肌显像(χ2=8.69,P＜0.05)和运动心肺比值(HLRex)(χ2=4.107,P＜0.05),其中最重要的是 HLRex。当 HLRex<1.5时CE 发生的危险性明显升高(相对危险度9.505,P＜0.05)。结论 99mTc-N-NOET MPI 可作为预测可疑或确诊 CAD 患者发生 CE 的无创性检查方法;根据HLRex的大小可有效区分高危和低危患者。 |
| 英文摘要: |
| Objective To analyze the prognostic value of 99mTc-N-NOET myocardial perfusion imaging (MPI) in patients with suspected or diagnosed coronary artery disease (CAD). Methods One hundred and eleven patients underwent 99mTc-N-NOET exercise and delay Gated MPI (GMPI), and followed by investigation of cardiac events (CE). Results Over an average follow-up time is 33.47±7.69 months, CE occurred in 10 patients. Univariate analyses and Multivariate stepwise Logistic regression analyses revealed that the abnormal myocardial imaging (χ2=8.69, P＜0.05) and HLRex (χ2=4.107, P＜0.05) were predictive value for occurrence of subsequent CE, moreover, HLRex was the only variable with independent predictive value for occurrence of subsequent CE. HLRex less than 1.5 was associated with a significantly increased frequency of subsequent CE (relative risk ratio was 9.505, P＜0.05). Conclusion 99mTc-N-NOET Ex-MPI is the most effective noninvasive technique that predicted the occurrence of CE in pts with suspected or diagnosed CAD. According to the size of HLRex, high-risk and low-risk pts can be effectively identified. |
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