| 申景涛,郭万华,辛小燕,徐佩,贾支俊,张颖.应用18F-FDG PET/CT探讨储尿刺激对脑功能的影响[J].中国医学影像技术,2008,24(5):763~765 |
| 应用18F-FDG PET/CT探讨储尿刺激对脑功能的影响 |
| Initial study on brain function affected by urine withholding stimulationwith 18F-FDG PET/CT |
| 投稿时间：2007-12-27 修订日期：2008-01-29 |
| DOI： |
| 中文关键词: 脑 排尿中枢 L-区 体层摄影术,发射型计算机 体层摄影术,X线计算机 18F 氟脱氧葡萄糖 |
| 英文关键词:Brain Pontine micturition centre L-region Tomography, emission computed Tomography, X-ray computed Fluorodeoxyglucose F18 |
| 基金项目:本课题受南京市卫生局2005年医学重点项目(ZKM05044)资助。 |
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| 中文摘要: |
| 目的 应用PET脑功能自动提取法研究18F-FDG PET显像受储尿刺激影响的脑解剖功能区。 方法 对25例正常人储尿和未储尿状态下分别进行18F-FDG PET/CT脑显像,应用脑功能自动提取法对比分析储尿前后18F-FDG脑显像的代谢变化,分析受储尿刺激影响的脑解剖功能核团。 结果 共22个脑解剖功能核团的代谢差异有统计学意义(P<0.05),其中双侧楔叶、左侧下枕回、左侧额中回、双侧额下回、双侧Brodmann17区、双侧Brodmann18区、双侧腹前核、右侧中央后回等13个核团代谢增高,同时左侧尾状核、双侧外侧核、左侧颞下回、左侧海马旁回、双侧胼胝体、左侧海马、左侧下丘脑等9个核团代谢降低。 结论 储尿刺激影响部分脑功能区代谢增高的同时使部分脑功能区代谢减低。18F-FDG PET/CT脑显像为临床研究泌尿中枢提供了功能-解剖学参考和重要的影像学方法。 |
| 英文摘要: |
| Objective To analysis the brain functional area with 18F-FDG metabolism imaging affected by urine withholding stimulation by brain functional area automatic extraction method. Methods PET/CT was separately performed in 25 healthy subjects with and without urine withholding, and then these images were compared by brain functional area automatic extraction method. The affected brain functional nucleus by urine withholding stimulation can be visualized. Results Significant difference was found in 22 brain functional areas. Among these 18F-FDG accumulation increased in the area like bilateral cuneus, left inferior occipital gyrus, left middle frontal gyrus, bilateral inferior frontal gyrus, bilateral Brodmann area 17, bilateral Brodmann area 18, bilateral ventral anterior nucleus and right postcentral gyrus, while in the area like left caudate, bilateral extra-nuclear, left inferior temporal gyrus, left parahippocampal gyrus, bilateral corpus callosum, left hippocampus and left hypothalamus, the 18F-FDG accumulation decreased. Conclusion The urine withholding stimulation can not only increase the 18F-FDG metabolism of some brain area, but also decrease the metabolism in some brain area. 18F-FDG PET/CT image can offer important functional-anatomic reference and a useful instrument for investigating uropoiesis center clinically. |
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