吴长君,王心宇,张春梅,范春艳,张雪菊,邱前义.定量组织速度成像技术对重度妊娠高血压综合征患者左心功能及胎儿心脏功能的研究[J].中国医学影像技术,2008,24(5):665~669
定量组织速度成像技术对重度妊娠高血压综合征患者左心功能及胎儿心脏功能的研究
Study on the cardiac function of the patients with severe pregnancy incuced hypertension and the fetus by quantitative tissue velocity imaging
投稿时间:2007-01-17  修订日期:2008-03-07
DOI:
中文关键词:  组织多普勒成像  妊娠高血压综合征  心室功能  Tei指数
英文关键词:Tissue Doppler imaging  Pregnancy incuced hypertension  Ventricular function  Tei index
基金项目:
作者单位E-mail
吴长君 哈尔滨医科大学第一临床医院超声科,黑龙江 哈尔滨 150001 zhangcm888@tom.com 
王心宇 哈尔滨医科大学第一临床医院超声科,黑龙江 哈尔滨 150001  
张春梅 哈尔滨医科大学第一临床医院超声科,黑龙江 哈尔滨 150001  
范春艳 哈尔滨医科大学第一临床医院超声科,黑龙江 哈尔滨 150001  
张雪菊 哈尔滨医科大学第一临床医院超声科,黑龙江 哈尔滨 150001  
邱前义 哈尔滨医科大学第一临床医院超声科,黑龙江 哈尔滨 150001  
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中文摘要:
       目的 应用定量组织速度成像技术评价重度妊娠高血压综合征(妊高征)患者的左心室功能及胎儿心脏功能。 方法 测定30例重度妊高征患者和60例健康初产妇常规超声心动图参数及二尖瓣环各部位收缩期及舒张早期和舒张晚期峰值速度(Vs、Ve、Va),同时测算胎儿右心室Tei指数。 结果 ①重度妊高征组IVS、LVPW、HR和左房前后径(LAD)较对照组显著增加;LVDd、LVEF和SV两组间比较差异无统计学意义。妊高征组二尖瓣口血流频谱E峰流速VE、A峰流速VA和左室等容舒张时间(IVRT)显著增加,VE/VA则显著降低。②二尖瓣环各位点组织速度两组间比较差异有统计学意义,重度妊高征组Vs低于对照组;Ve值除后间隔外均显著低于对照组;Va值除前间隔外均高于对照组。③重度妊高征组胎儿的(IRT+ICT)和Tei指数显著高于对照组,ET亦高于对照组,但无统计学意义。 结论 ①重度妊高征患者左心室收缩和舒张功能因心肌损害程度及发病时间的不同而有不同程度减低。②QTVI对诊断重度妊高征引起的左心室收缩和舒张功能变化较为敏感。③重度妊高征不仅会影响母体心脏功能,且对胎儿心脏功能亦有影响。
英文摘要:
      Objective To investigate the left cardiac and the fetal cardiac function of the patients with severe pregnancy incuced hypertension (PIH) by quantitative tissue velocity imaging (QTVI). Methods Thirty patients with severe PIH and 60 healthy primiparas were performed echocardiography. After the conventional parameters were measured, the peak velocity of the systolic phase (Vs), the peak velocity of early stage and advanced stage of diastolic phase (Ve, Va) by QTVI were obtained at the mitral annulus, and the Tei index of the right ventricle of the fetus were caculated simutanousely. Results ①The parameters of inter-ventricle septum (IVS), left ventricular posterior wall (LVPW), heart rate (HR) and left atrial diameter (LAD) in severe PIH group increased more obviously than the control group, but there was no significant difference on the parameters of left ventricular diastolic diameter (LVDd), left ventricular ejection fraction (LVEF) and stroke volume (SV) between the two groups. The velocity of E peak and A peak of the mitral flow (VE, VA) and the isovolumic relaxation time (IVRT) increased significantly in the PIH group, but VE/VA decreased notablely. ② There was statistical difference on the tissue velocity of the mitral annulus between the two groups. Vs in PIH group was lower than the control group, and Ve was lower markedly except the posterior septum, and Va was higher except the anterior septum. ③Isovolumic relaxation time and isovolumil contraction time (IRT+ICT) and Tei index in PIH group were higher than the control group significantly, and ejection time (ET) was also higher in the PIH group, but the difference was not obvious. Conclusion ① The systolic and diastolic function of left ventricle in the patients with severe PIH decreased at different degree because of the different myocardial damage and onset time. ② It was sensitive to diagnosis the change of the systolic and diastolic function of left ventricle in the severe PIH with QTVI. ③ Severe PIH affected not only the cardiac function of the mother but also that of the fetus.
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