武靖,蒋全胜,洪楠,邸强.高压氧治疗SARS后Ⅰ期股骨头缺血性坏死的随诊研究[J].中国医学影像技术,2008,24(4):608~610
高压氧治疗SARS后Ⅰ期股骨头缺血性坏死的随诊研究
The effect of hyperbaric-oxygen-therapy on stage Ⅰ avascular necrosis of femoral head in SARS patients
投稿时间:2007-12-31  修订日期:2008-03-13
DOI:
中文关键词:  高压氧  严重急性呼吸道综合征  股骨头坏死  缺血
英文关键词:Hyperbric-oxygen  Severe acute respiratory syndrome  Femur head necrosis  Ischemia
基金项目:
作者单位E-mail
武靖 北京大学人民医院放射科,北京 100044  
蒋全胜 北京大学人民医院放射科,北京 100044  
洪楠 北京大学人民医院放射科,北京 100044 hongnan@bjmu.edu.cn 
邸强 北京大学人民医院放射科,北京 100044  
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中文摘要:
      目的 通过对15例SARS后被确诊为Ⅰ期骨缺血坏死后行高压氧治疗病例的追踪研究,探讨高压氧治疗SARS后Ⅰ期股骨头缺血坏死的疗效。方法 符合WHO确定的SARS诊断标准的15例患者(23髋)行双侧股骨头影像学检查,其中平片、CT检查为阴性, MRI诊断为Ⅰ期股骨头缺血性坏死。高压氧治疗后,随诊34个月,对比治疗前后平片、CT和MRI结果。结果 在高压氧治疗前,所有患者股骨头缺血性坏死情况根据1992年国际骨循环联合会(ARCO)国际分期标准均诊断为Ⅰ期,高压氧治疗后随访近3年,无痊愈者,2例(3髋)进展为Ⅳ期,1例(1髋)进展为Ⅲ期, 12患者(19髋)进展为Ⅱ期。结论 高压氧治疗不能逆转或有效阻止SARS后Ⅰ期股骨头缺血性坏死的进展。
英文摘要:
      Objective To evaluate the treatment outcome of hyperbaric-oxygen-therapy on stage Ⅰ avascular necrosis of the femoral heads (AVN) in SARS patients. Methods Fifteen patients (23 hips) who fitted the WHO case definition for SARS were identified to have stage Ⅰ AVN by MRI. No abnormality could be found in conventional radiographs and CT of the hips. All patients underwent the HBO therapy. After 34 months we compared the results of X-ray, CT and MRI. Results Before the treatment of HBO, all of the patients with AVN of femoral heads were at stage Ⅰ according to the system of Steinberg. After about 3 years follow-up, none of the hips with AVN demonstrated evidence of complete resolution. Two patients (3 hips) progressed to stage Ⅳ AVN, one patient (1 hip) progressed to stage Ⅲ AVN; other patients (12 patients, 19 hips) progressed to stage Ⅱ AVN; Conclusion HBO can not heal or prevent the progress of avascular necrosis of the femoral head in SARS patients.
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