| 陈楠,李坤成,刘佳宾,秦文.Balo同心圆硬化的磁共振表现特征及其病理基础[J].中国医学影像技术,2008,24(4):514~516 |
| Balo同心圆硬化的磁共振表现特征及其病理基础 |
| Balo's concentric sclerosis: a correlative study of MRI and pathologic feature |
| 投稿时间：2007-12-18 修订日期：2008-03-20 |
| DOI： |
| 中文关键词: 脱髓鞘疾病 磁共振成像 病理学,临床 |
| 英文关键词:Demyelinating diseases Magnetic resonance imaging Pathology, clinical |
| 基金项目: |
|
| 摘要点击次数: 2121 |
| 全文下载次数: 841 |
| 中文摘要: |
| 目的 探讨Balo同心圆硬化(BCS)的磁共振表现特征及其病理基础。方法 回顾性分析4例经大脑立体定向活检证实的BCS的MRI及其病理表现,其中增强扫描2例,头颅CT检查1例。 结果 4例患者中,1例单发,3例多发,最多者病灶6个。病变主要累及大脑半球皮层下和深部白质区,共发现13个病灶,其中顶叶半卵圆中心和颞叶的发病比例高。典型同心圆样病灶9个,直径1~2.2 cm,同心圆层数为3~6个。 在T1WI加权像呈等、低信号相间;T2WI/Flair/ADC 像上呈等、高信号交替环,病灶周围有轻度水肿表现,上述表现与镜下脱髓鞘区与髓鞘保留区相间相对应。其余4个不典型的病灶呈斑片状或煎蛋样改变,但在病灶内均可见1~4个半环样结构;增强后1例病灶呈点状或边缘线状强化。 结论 MRI能反映BCS的病理特征,对BCS活体、无创诊断具有重要意义。 |
| 英文摘要: |
| Objective To evaluate the correlation between the features on MR and pathologic finding of the Balo’s concentric sclerosis (BCS). Methods Four patients of BCS were reviewed on the basis of brain MRI and stereotactic brain biopsy. Results Of the 4 cases,thirteen lesions showed on MRI. Solitude lesion and multitude lesions occourred in 1 case and 3 cases, respectively. They mainly distributed on the subcortex of cerebral hemispheres and deep part white matter, especially located at centrum ovale and temporal lobe. Among them, nine lesions appeared as characteristic concentric structure. T1-weighted revealed 3－6 concentric rings with diameters ranging from 1 to 2.2 cm alternating between hypo- and iso-intensity signal zones. On T2-weighted, fluid-attenuated inversion-recovery pulse sequence (FLAIR) and diffusion weighted imaging (DWI), the above-mentioned rings focus appeared as iso-and hyper-intensity signal with slightly surrounding swelling and poorly defined margin. The diameters were slightly longer than on T1WI, this finding being consistent with pathological results. Four atypia lesions showed as patching or fried egg. There was 1 to 4 semi-circumi structure within the lesion. On Gd-DTPA enhanced MR scans, lightly liner-like enhancement occurred in one patient. Conclusion MRI has the characteristic findings which present the pathologic changes of BCS, so it is very useful in diagnosis of BCS during lifetime. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
