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庞鹏飞,朱康顺,孟晓春,关守海,姜在波,李征然,何可可,单鸿.NBCA栓塞治疗食道胃静脉曲张后门静脉血流动力学变化的定量研究[J].中国医学影像技术,2008,24(3):434~437

NBCA栓塞治疗食道胃静脉曲张后门静脉血流动力学变化的定量研究

Quantitative research about hemodynamics of portal system after transcatheter embolization with NBCA for the treatment of esophagogastric varices

投稿时间：2007-12-24 修订日期：2008-03-03

DOI：

中文关键词: 门静脉高压血流动力学食道胃静脉曲张栓塞,治疗性

英文关键词:Portal hypertension Hemodynamics Esophagogastric varices Embolization, therapeutic

基金项目:

作者	单位	E-mail
庞鹏飞	中山大学附属第三医院放射科,广东广州 510630
朱康顺	中山大学附属第三医院放射科,广东广州 510630
孟晓春	中山大学附属第三医院放射科,广东广州 510630
关守海	中山大学附属第三医院放射科,广东广州 510630
姜在波	中山大学附属第三医院放射科,广东广州 510630
李征然	中山大学附属第三医院放射科,广东广州 510630
何可可	中山大学附属第三医院放射科,广东广州 510630
单鸿	中山大学附属第三医院放射科,广东广州 510630	gzshsums@public.guangzhou.gd.cn

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中文摘要:

目的定量研究NBCA栓塞治疗食道胃静脉曲张后门静脉血流动力学的变化。方法 30例肝硬化反复上消化道出血患者,男性25例,女性5例。应用NBCA栓塞治疗食道胃静脉曲张,测定栓塞前后门静脉压力及门静脉灌注量的变化。结果栓塞后30例患者门静脉压力由术前(33.90±8.09)cmH₂O上升至术后(38.43±8.42)cmH₂O(P＜0.001)。脾静脉压力由术前(33.53±7.56)cmH₂O上升至术后(36.87±7.87)cmH₂O(P＜0.001)。肠系膜上静脉压力由术前(33.13±7.16)cmH₂O上升至术后(36.57±7.74)cmH₂O(P＜0.001)。术后1周12例患者门静脉灌注量由术前(0.7439±0.1627)ml·min^-1·ml^-1上升至术后(0.8830±0.1526)ml·min^-1·ml^-1(P＜0.001),门静脉灌注指数由术前0.6129±0.0422上升至术后0.7202±0.0506(P＜0.001)。结论 NBCA栓塞治疗食道胃静脉曲张后,门静脉压力升高,门静脉灌注得到改善。

英文摘要:

Objective To evaluate the hemodynamics change of portal system after transcatheter embolization with NBCA for the treatment of bleeding from esophagogastric varices. Methods Thirty patients (25 males,5 females) of liver cirrhosis with esophagogastric varices who suffered from repeated upper gastrointestinal bleeding were included in this study. Catheter insertion and embolization of esophagogastric varices were completed in all 30 patients. The common 5F-catheter was inserted into portal vein, splenic vein, superior mesenteric vein respectively and pressure were measured before and after transcatheter embolization. The portal vein perfusion and portal perfusion index of 12 patients were measured before operation and after one week. Results The pressure of portal veins significantly raised from (33.90±8.09) cmH₂O before transcatheter embolization to (38.43±8.42) cmH₂O after transcatheter embolization (P＜0.001). The pressure of splenic veins significantly raised from (33.53±7.56) cmH₂O to (36.87±7.87) cmH₂O (P＜0.001). The pressure of superior mesenteric veins significantly raised from (33.13±7.16) cmH₂O to (36.57±7.74) cmH₂O (P＜0.001). The portal vein perfusion of 12 patients significantly raised from (0.7439±0.1627) ml·min^-1·ml^-1 before operation to (0.8830±0.1526) ml·min^-1·ml^-1 after one week (P＜0.001). The portal perfusion index of 12 patients significantly raised from (0.6129±0.0422) to (0.7202±0.0506) (P＜0.001). Conclusion The portal vein perfusion of the liver will be improved with the rising of the pressure of the portal vein after transcatheter embolization of esophagogastric varices.

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