| 张连娜,彭京京,刘洪洪,杨芳,蔡槱伯.201Tl显像在良恶性软组织肿瘤诊断中的应用[J].中国医学影像技术,2008,24(1):127~130 |
| 201Tl显像在良恶性软组织肿瘤诊断中的应用 |
| Application of 201-Thallium scintigraphy for malignant or benign soft tissue lesions |
| 投稿时间：2007-09-01 修订日期：2007-11-04 |
| DOI： |
| 中文关键词: 铊放射性同位素 放射性核素显像 结缔和软组织 肿瘤 单光子发射型计算机断层仪 |
| 英文关键词:Thallium radioisotopes Radionuclide imaging Bone tissue Neoplasm connective and soft tissue SPECT |
| 基金项目: |
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| 中文摘要: |
| 目的 探讨201Tl显像及其半定量分析在软组织良性恶肿瘤诊断中的应用价值。方法 回顾性研究骨肿瘤科66例肢体软组织肿瘤及瘤样病变的201Tl显像临床资料,利用ROI技术对其进行半定量分析,所有病例均经手术或病理组织学证实。结果 201Tl双时相显像对肢体软组织肿瘤良恶性诊断的灵敏度,特异性和准确性分别为89.2%(33/37)、82.8%(24/29)、86.4%(57/66)。早期相恶性肿瘤组T/NTe值为3.02±1.74,明显高于良性肿瘤组(1.62±0.84)(P<0.05);延迟相恶性肿瘤组T/NTd值为2.34±1.28,明显高于良性肿瘤组1.26±0.46(P<0.05)。结论 201Tl双时相显像是一种方便、无创的检查方法。在鉴别软组织良、恶性肿瘤的应用方面具有较高的临床诊断价值。 |
| 英文摘要: |
| Objective To investigate the value of thallium-201-chloride (201Tl) scans and semi-quantitative assessment in the differential diagnosis of soft tissue tumors in extremity. Methods 201Tl scans was performed in 66 patients with soft tissue tumors. Technique of ROI was used for semi-quantitative assessment. All the cases were confirmed by surgery and histopathological examinations. Results The sensitivity, specificity, and accuracy of 201Tl scans were 89.2%, 82.8%, and 86.4%, respectively. The early T/NTe of malignant lesions (3.02±1.74) were higher than benign lesions (1.62±0.84)(P<0.05). The delay T/NTd of malignant lesions (2.34±1.28) were higher than benign lesions (1.26±0.46)(P<0.05). Conclusion These results support the notion that 201Tl scintigraphy, although showing some false-positive and false-negative findings, is a useful tool in the evaluation of either malignant tumors or benign lesions. |
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