| 张泉,张云亭,冯凯琳,张敬,李威,张权.MR扩散张量成像在海马硬化术前诊断中的价值研究[J].中国医学影像技术,2008,24(1):41~43 |
| MR扩散张量成像在海马硬化术前诊断中的价值研究 |
| Study on MR-diffusion tensor imaging in preoperative diagnosis of hippocampal sclerosis |
| 投稿时间：2007-10-14 修订日期：2007-12-20 |
| DOI： |
| 中文关键词: 海马 硬化 扩散张量成像 |
| 英文关键词:Hippocampus Sclerosis Diffusion tensor imaging |
| 基金项目: |
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| 中文摘要: |
| 目的 探讨海马硬化患者的扩散张量成像(DTI)参数变化特点,并评价DTI在海马硬化术前诊断中的价值。方法 对8例单侧海马硬化患者和32例健康志愿者行常规MRI和DTI检查,定量测量双侧海马的平均扩散系数(DCavg)、部分各向异性(FA)、1-容积比(1-VR)和相对各向异性(RA)值并统计。结果 正常人双侧海马之间DCavg、FA、1-VR和RA均无显著性差异。海马硬化患者患侧海马DCavg显著高于对侧海马和正常志愿者,患侧海马FA显著低于对侧海马和正常志愿者,患侧海马1-VR和RA显著低于正常志愿者,但患侧海马1-VR和RA与对侧海马无显著性差异。结论 DTI是海马硬化定侧诊断的有效方法,DCavg升高、FA减低能够作为海马硬化术前诊断的有用指标。 |
| 英文摘要: |
| Objective To investigate the diffusion characteristics of hippocampi in patients with hippocampal sclerosis and to study the value of diffusion tensor imaging (DTI) in preoperative diagnosis of hippocampal sclerosis.Methods Eight patients of unilateral hippocampal sclerosis and 32 healthy volunteers underwent conventional and DTI scanning. The DCavg, FA, 1-VR and RA of bilateral hippocampi were measured respectively.Results No significant differences of DCavg, FA, 1-VR and RA were noted between right and left hippocampi in the control. The DCavg of ipsilateral hippocampi was higher than that of contralateral side and the control. The FA of ipsilateral hippocampi was lower than that of contralateral side and the control. The 1-VR and RA of ipsilateral hippocampi were higher than that of the control, but no significant differences of 1-VR and RA were noted between ipsilateral side and contralateral side. Conclusion DTI is a valuable technique and the increased DCavg, decreased FA can be used as useful indexes of lateralizing the epileptogenic lesion in patients with hippocampal sclerosis before operation. |
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