| 李军,李歌,吕冰梅,孙庆利,徐雨霞.造血干细胞移植后急性移植物抗宿主病的超声改变[J].中国医学影像技术,2007,23(12):1850~1852 |
| 造血干细胞移植后急性移植物抗宿主病的超声改变 |
| Diagnostic value of abdominal ultrasonogram in hemopoietic stem cell transplantation patients with acute graft versus host disease |
| 投稿时间：2007-07-10 修订日期：2007-09-08 |
| DOI： |
| 中文关键词: 造血干细胞移植 急性移植物抗宿主病 超声检查 |
| 英文关键词:Hemopoietic stem cell transplantation Acute graft versus host disease Ultrasonography |
| 基金项目: |
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| 中文摘要: |
| 目的 阐述血液病患者造血干细胞移植(HSCT)治疗后并发急性移植物抗宿主病(aGVHD)的腹部超声改变,探讨其在aGVHD诊断中的临床意义。方法 对73例HSCT患者进行常规腹部超声检查,比较分析aGVHD患者(43例)及无aGVHD患者(30例)的肝脏、胆囊、胰腺、脾脏、肾脏及肠道声像图变化特征。结果 aGVHD患者出现弥漫性肝实质损害、胆囊壁增厚、胆汁淤积、脾脏体积增大及肠蠕动异常等一系列超声变化,与无aGVHD患者比较存在明显差异(P＜0.05)。结论 HSCT治疗后并发aGVHD患者的腹部超声改变有特异性,能够为aGVHD的临床诊断提供较为可靠的影像学依据。 |
| 英文摘要: |
| Objective To investigate the ultrasonic diagnosis of abdominal ultrasonogram in patients with acute graft versus host disease(aGVHD) who receive allogenic hemopoietic stem cell transplantation(Allo-HSCT). Methods We regularly practiced abdominal ultrasound examination weekly in 73 Allo-HSCT patients, and contrasted the ultrasonographic characteristics in 43 aGVHD patients with those in 30 patients who did not present aGVHD. Results As compared with those of the control group, the abdominal ultrasonic images of the aGVHD patients obviously changed (P＜0.05), including increased spleen volume, gallbladder wall thickening, cholestasis, liver diffuse parenchyma lesions,and abnormal enterokinesia. Conclusion The conventional abdominal ultrasound examination in Allo-HSCT patients provides reliable diagnosis evidence of aGVHD. |
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