| 胡佳琪,石华,郭瑞强,郝力丹,陈文卫.多巴酚丁胺负荷试验时应变率检测冠心病的价值[J].中国医学影像技术,2007,23(9):1317~1319 |
| 多巴酚丁胺负荷试验时应变率检测冠心病的价值 |
| Value of strain rate in detecting coronary heart disease during Dobutamine stress echocardiography test |
| 投稿时间：2007-04-19 修订日期：2007-06-09 |
| DOI： |
| 中文关键词: 冠心病 负荷试验 多巴酚丁胺 应变率 |
| 英文关键词:Coronary heart disease Stress Dobutamine Strain rate |
| 基金项目: |
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| 中文摘要: |
| 目的 探讨应变率技术结合多巴酚丁胺负荷试验(DSE)检测冠心病的价值。方法 对28例可疑冠心病患者进行大剂量DSE,测量收缩期最大应变率(SRs)、舒张早期峰值应变率(SRe)和舒张晚期峰值应变率(SRa)。结果 冠心病组SRs随着Dob量的增加而逐渐增大;而SRe 20、30、40 μg·kg-1·min-1时较静息显著减低。SRs 30、40 μg·kg-1·min-1时低于同一注药速度正常组;SRe在各阶段均低于正常组。结论 DSE与应变率结合定量评价局部心肌运动变化,为临床诊断冠心病提供了有价值的信息。 |
| 英文摘要: |
| Objective To explore the value of strain rate and Dobutamine stress echocardiography (DSE) in the diagnosis of coronary heart disease. Methods High-dose DSE was performed in 28 patients who were suspected having coronary heart disease (CHD). By strain rate technology, systolic peak strain rate (SRs), peak early diastolic strain rate (SRe) and peak late diastolic strain rate (SRa) was measured. Results In patients with CHD, SRs enhance by the increasement of dose of DSE, and SRe on 20, 30, 40 μg·kg-1·min-1 are all lower than that on baseline. On 30 and 40 μg·kg-1·min-1, SRs of CHD group are lower than that of normal group at the same Dobutamine dose. And at any dose, SRe of myocardial segments perfused by stenotic coronary artery were lower than that of segments perfused by normal coronary artery during DSE. Conclusion Combining strain rate and DSE to quantify local myocardial motion is valuable to offer many important clinic messages, and improves the diagnosis of coronary heart disease. |
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