| 王小玲,于铁链,李建龙,王瑞敏.短暂性脑缺血患者脑供血动脉病变及Willis环的MRA评估[J].中国医学影像技术,2007,23(9):1278~1281 |
| 短暂性脑缺血患者脑供血动脉病变及Willis环的MRA评估 |
| Cerebral arterial lesions and the circle of Willis in TIA patients: a preliminary study with MRA |
| 投稿时间：2007-05-11 修订日期：2007-06-15 |
| DOI： |
| 中文关键词: 脑缺血发作,短暂性 磁共振成像 脑供血动脉 大脑动脉环 |
| 英文关键词:Ischemic attacks, transient Magnetic resonance imaging Cerebral feeding artery Circle of Willis |
| 基金项目:本课题受天津市自然科学基金资助(033611711)。 |
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| 中文摘要: |
| 目的 评估短暂性脑缺血发作(TIA)患者供血动脉病变分布及Willis环组成血管。方法 41例TIA患者为研究对象,与30例正常人及30例脑梗死患者进行对照。用3D CE-MRA和3D TOF MRA分析头颈部供血动脉病变和Willis环组成血管。结果 TIA组供血动脉病变同时累及Willis环前动脉 、环后动脉(包括大脑前动脉(ACA)、大脑中动脉(MCA)和大脑后动脉(PCA))的情况较梗死组减少(P＝0.001)。单侧VA发育不良伴动脉硬化者在颈动脉(ICA)系统TIA组和V-BA系统TIA组均较正常组多见(P=0.045;P=0.018)。ACA A1段发育不良或缺如在ICA系统TIA组较V-BA系统TIA及正常组更常见(P＝0.001;P＝0.012)。存在Willis环前供血动脉严重病变的病例中,TIA组后交通动脉(PCoA)显示率明显高于脑梗死组(P=0.046)。前交通动脉(ACoA)、PCoA同时显示在TIA组较脑梗死组更常见(P=0.003)。结论 脑梗死组较TIA组存在更多的Willis环后动脉病变。单侧VA发育不良伴动脉硬化可能是TIA发生的危险因素。A1段发育不良或缺如可能是ICA系统TIA发生的易感因素。ACoA、PCoA同时存在对维持脑供血起代偿作用。 |
| 英文摘要: |
| Objective To evaluate the distribution of cerebral arterial lesions and the vessels of the circle of Willis in TIA patients with MRA. Methods Forty-one TIA patients were chosen as invested subjects and 30 healthy subjects and 30 stoke patients were chosen as control subjects. 3D CE-MRA (for intracranial and extracranial artery) and 3D TOF MRA (for the circle of Willis) were performed. The lesions of cerebral arteries and the condition of vessels of the circle of Willis were analyzed. Results The cases that arterial lesions not only involved CCA-ICA and/or V-BA but also involved ACA, MCA, and PCA were less in the TIA group than that in stroke group (P＝0.001). Unilateral dysplastic VA accompanied with arteriosclerosis were more often in ICA-TIA and V-BA TIA than that in healthy group (P=0.045;P=0.018). Dysplasia or absence of A1 segment of ACA in ICA-TIA system was more often, and had a significant difference compared with V-BA TIA system and healthy group (P＝0.001;P＝0.012). PCoA was more often present in TIA patients with severe ICA and/or BA stenosis than that in stroke patients with the same severe stenosis (P=0.046). The simultaneously presenting rate of both ACoA and PCoA in TIA group was higher than that in stroke group (P＝0.003). Conclusion Stroke patients had more ACA, MCA, and/or PCA stenosis than TIA patients. Unilateral dysplastic VA accompanied with arteriosclerosis may be a risk factor for TIA. Dysplasia or absence of A1 segment of ACA may be a risk factor for ICA-TIA. The presence of both ACoA and PCoA may play a protective role in ischemic cerebrovascular disease. |
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